Evidence map›Paper›PMID 29915574›Full record

ArticleFrontiers in immunology2018

A Recombinant Fragment of Human Surfactant Protein D induces Apoptosis in Pancreatic Cancer Cell Lines

Anuvinder Kaur, Muhammad Suleman Riaz, Valarmathy Murugaiah, Praveen Mathews Varghese, Shiv K Singh, Uday Kishore

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

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  5. The C-Type Lectin Receptors.Advances in experimental medicine and biology · 2025
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  10. Hyaluronic Acid as a Modern Approach in Anticancer Therapy-Review.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Anuvinder KaurBiosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Muhammad Suleman RiazBiosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Valarmathy MurugaiahBiosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Praveen Mathews VargheseBiosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Shiv K SinghDepartment of Gastroenterology and Gastrointestinal Oncology, University Medical Center, Goettingen, Germany.
Uday KishoreBiosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Brunel University of London · GBUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human surfactant protein D (SP-D) is a potent innate immune molecule, which is emerging as a key molecule in the recognition and clearance of altered and non-self targets. Previous studies have shown that a recombinant fragment of human SP-D (rfhSP-D) induced apoptosis

Indexed as

ApoptosisCaspase 3Caspase 8Cell Cycle CheckpointsCell Line, Tumorfas ReceptorHumansNF-kappa BPancreatic NeoplasmsPeptide FragmentsProtein TransportPulmonary Surfactant-Associated Protein DRecombinant ProteinsSignal TransductionTOR Serine-Threonine KinasesTumor Suppressor Protein p53Caspase 3Caspase 8fas ReceptorNF-kappa BPeptide FragmentsPulmonary Surfactant-Associated Protein DRecombinant ProteinsTOR Serine-Threonine KinasesTumor Suppressor Protein p53apoptosisimmune surveillanceinnate immunitypancreatic cancersurfactant protein D

Identifiers

PMID29915574
PMCPMC5994421
OpenAlexW2799608602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.