Evidence map›Paper›PMID 29915544›Full record

ArticleFrontiers in physiology2018

Involvement of GABAergic and Adrenergic Neurotransmissions on Paraventricular Nucleus of Hypothalamus in the Control of Cardiac Function.

Michelle M Mendonça, Joice S Santana, Kellen R da Cruz, Danielle Ianzer, Paulo C Ghedini, Eugene Nalivaiko, Marco A P Fontes, Reginaldo N Ferreira, Gustavo R Pedrino, Diego B Colugnati and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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  7. Contribution of DNA methylation in chronic stress-induced cardiac remodeling and arrhythmias in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Michelle M MendonçaDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Joice S SantanaDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Kellen R da CruzDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Danielle IanzerDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Paulo C GhediniDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Eugene NalivaikoNeurocardiology Laboratory, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
Marco A P FontesDepartment of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Reginaldo N FerreiraDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Gustavo R PedrinoDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Diego B ColugnatiDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Carlos H XavierDepartment of Physiological Sciences, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Universidade Federal de Goiás · BRUniversidade Federal de Minas Gerais · BRUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sympathetic premotor neurons of the paraventricular hypothalamus (PVN) play a role in hemodynamics adjustments during changes in body fluid homeostasis. However, PVN contribution to the tonic control of cardiac function remains to be systematically studied. In this study, we assessed whether GABAergic and adrenergic synapses, known for being active in the PVN, are involved in the control of cardiac function. Adult male Wistar rats (250-350 g;

Indexed as

autonomic nervous systemcardiac contractilitycardiac functionparaventricular nucleussympathetic nervous system

Identifiers

PMID29915544
PMCPMC5994789
OpenAlexW2806293507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.