Evidence map›Paper›PMID 29915366›Full record

ArticleScientific reports2018

Spatio-temporal modelling of weekly malaria incidence in children under 5 for early epidemic detection in Mozambique.

Kathryn L Colborn, Emanuele Giorgi, Andrew J Monaghan, Eduardo Gudo, Baltazar Candrinho, Tatiana J Marrufo, James M Colborn

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathryn L ColbornDepartment of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Kathryn.Colborn@ucdenver.edu.
Emanuele GiorgiLancaster Medical School, Lancaster University, Lancaster, UK.ORCID 0000-0003-0640-181X
Andrew J MonaghanNational Center for Atmospheric Research, Boulder, CO, USA.
Eduardo GudoInstituto Nacional de Saude, Maputo, Mozambique.
Baltazar CandrinhoNational Malaria Control Program, Maputo, Mozambique.
Tatiana J MarrufoInstituto Nacional de Saude, Maputo, Mozambique.
James M ColbornClinton Health Access Initiative, Boston, MA, USA.

Funding

Medical Research Council MR/M015297/1
6 · The paper itself

Abstract

Malaria is a major cause of morbidity and mortality in Mozambique. We present a malaria early warning system (MEWS) for Mozambique informed by seven years of weekly case reports of malaria in children under 5 years of age from 142 districts. A spatio-temporal model was developed based on explanatory climatic variables to map exceedance probabilities, defined as the predictive probability that the relative risk of malaria incidence in a given district for a particular week will exceed a predefined threshold. Unlike most spatially discrete models, our approach accounts for the geographical extent of each district in the derivation of the spatial covariance structure to allow for changes in administrative boundaries over time. The MEWS can thus be used to predict areas that may experience increases in malaria transmission beyond expected levels, early enough so that prevention and response measures can be implemented prior to the onset of outbreaks. The framework we present is also applicable to other climate-sensitive diseases.

Indexed as

Child, PreschoolClimateEpidemicsGeographyHumansIncidenceMalariaModels, StatisticalMozambique

Identifiers

PMID29915366
PMCPMC6006329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.