ReviewHeredity2018
Recent advances in vertebrate and invertebrate transgenerational immunity in the light of ecology and evolution.
Review in Heredity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 121 citations in OpenAlex.
- Trained immunity in farm animals.Veterinary research · 2025Review
- Sex-dependent effects of infection on guppy reproductive fitness and offspring parasite resistance.The Journal of animal ecology · 2025Article
- Parental influence on brown trout offspring immune cell composition: An infection study with Tetracapsuloides bryosalmonae.PloS one · 2025Article
- Evidence for trans-generational immune priming againstFrontiers in immunology · 2025Article
- Multigenerational inheritance of parasitic stress memory inEnvironmental epigenetics · 2025Article
- Parent-Specific Transgenerational Immune Priming Enhances Offspring Defense-Unless Heat Stress Negates It All.Ecology and evolution · 2024Article
- Epigenetic control and inheritance of rDNA arrays.bioRxiv : the preprint server for biology · 2024Article
- Are fish immunocompetent enough to face climate change?Biology letters · 2024Review
- Chytrid infections exhibit historical spread and contemporary seasonality in a declining stream-breeding frog.Royal Society open science · 2024Article
- Inheritance of Stress Responses via Small Non-Coding RNAs in Invertebrates and Mammals.Epigenomes · 2023Review
- The Role of Human and Animal Monocytes and Macrophages in Homeostasis and Disease.International journal of molecular sciences · 2023Article
- Transgenerational plasticity in a zooplankton in response to elevated temperature and parasitism.Ecology and evolution · 2023Article
- Article
- Infection by a helminth parasite is associated with changes in DNA methylation in the house sparrow.Ecology and evolution · 2022Article
- Parasite resistance and parasite tolerance: insights into transgenerational immune priming in an invertebrate host.Biology letters · 2022Article
- Reproductive consequences of transient pathogen exposure across host genotypes and generations.Ecology and evolution · 2022Article
- The microbiome: A heritable contributor to bone morphology?Seminars in cell & developmental biology · 2022Review
- Maternal age and maternal environment affect egg composition, yolk testosterone, offspring growth and behaviour in laying hens.Scientific reports · 2022Article
- Review
- Early queen infection shapes developmental dynamics and induces long-term disease protection in incipient ant colonies.Ecology letters · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parental experience with parasites and pathogens can lead to increased offspring resistance to infection, through a process known as transgenerational immune priming (TGIP). Broadly defined, TGIP occurs across a wide range of taxa, and can be viewed as a type of phenotypic plasticity, with hosts responding to the pressures of relevant local infection risk by altering their offspring's immune defenses. There are ever increasing examples of both invertebrate and vertebrate TGIP, which go beyond classical examples of maternal antibody transfer. Here we critically summarize the current evidence for TGIP in both invertebrates and vertebrates. Mechanisms underlying TGIP remain elusive in many systems, but while it is unlikely that they are conserved across the range of organisms with TGIP, recent insight into epigenetic modulation may challenge this view. We place TGIP into a framework of evolutionary ecology, discussing costs and relevant environmental variation. We highlight how the ecology of species or populations should affect if, where, when, and how TGIP is realized. We propose that the field can progress by incorporating evolutionary ecology focused designs to the study of the so far well chronicled, but mostly descriptive TGIP, and how rapidly developing -omic methods can be employed to further understand TGIP across taxa.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.