ArticleScientific reports2018
Vector competence of Haemaphysalis longicornis ticks for a Japanese isolate of the Thogoto virus.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
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- A novel accessory gene product of tick-borne Dhori-Orthomyxovirus, encoded by overlooked spliced transcripts of RNA segment 6.Journal of virology · 2025Article
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- Human Tick-Borne Diseases and Advances in Anti-Tick Vaccine Approaches: A Comprehensive Review.Vaccines · 2024Review
- Diversity analysis of tick-associated viruses in northeast China.Virologica Sinica · 2023Article
- The known unknowns of Powassan virus ecology.Journal of medical entomology · 2023Review
- Comparative Study of Ten Thogotovirus Isolates and Their DistinctJournal of virology · 2022Article
- Evaluation of two artificial infection methods of live ticks as tools for studying interactions between tick-borne viruses and their tick vectors.Scientific reports · 2022Article
- Horizontal and Vertical Transmission of Powassan Virus by the Invasive Asian Longhorned Tick,Frontiers in cellular and infection microbiology · 2022Article
- Antiviral RNA interference in disease vector (Asian longhorned) ticks.PLoS pathogens · 2021Article
- Vector competence of human-biting ticks Ixodes scapularis, Amblyomma americanum and Dermacentor variabilis for Powassan virus.Parasites & vectors · 2021Article
- Emerging tick-borne pathogens of public health importance: a mini-review.Journal of medical microbiology · 2020Review
- Epidemiological Study of Thogoto and Dhori Virus Infection in People Bitten by Ticks, and in Sheep, in an Area of Northern Spain.International journal of environmental research and public health · 2020Article
- Failure of the Asian longhorned tick, Haemaphysalis longicornis, to serve as an experimental vector of the Lyme disease spirochete, Borrelia burgdorferi sensu stricto.Ticks and tick-borne diseases · 2020Article
- Characterization of an iron-inducible Haemaphysalis longicornis tick-derived promoter in an Ixodes scapularis-derived tick cell line (ISE6).Parasites & vectors · 2019Article
- A Continuing Exploration of Tick-Virus Interactions Using Various Experimental Viral Infections of Hard Ticks.Frontiers in physiology · 2018Review
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thogoto virus (THOV), a tick-borne arbovirus not previously reported in East Asia, was recently isolated from Haemaphysalis longicornis in Kyoto, Japan. In this study, we investigated the vector competence of H. longicornis ticks for a Japanese isolate of the Thogoto virus using anal pore microinjection and experimental virus acquisition. Our results showed that anal pore microinjection can readily infect adult ticks, and THOV-infected ticks can successfully transmit the virus to mice. Blood feeding was also critical in the distribution of the virus in tick organs, most especially in the salivary glands. Furthermore, co-feeding between an infected adult and naïve nymphs can also produce infected molted adults that can horizontally transmit THOV to mice. Altogether, our results suggest that H. longicornis is a competent vector for the Japanese THOV isolate and could be the primary tick vector of the virus in Japan.
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