Evidence map›Paper›PMID 29915156›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2018

Disposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of

David J Wagner, Laura M Shireman, Sojung Ahn, Danny D Shen, Joanne Wang

Open access · bronzeAbstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Cardiac Uptake of the Adrenergic Imaging AgentDrug metabolism and disposition: the biological fate of chemicals · 2024
    Article
  4. Review
  5. Drug metabolism and disposition: the biological fate of chemicals · 2022
    Article
  6. Article
  7. Methamphetamine Dysregulation of the Central Nervous System and Peripheral Immunity.The Journal of pharmacology and experimental therapeutics · 2021
    Review
  8. Article
  9. Development and validation of a LC-MS/MS method for in vivo quantification of meta-iodobenzylguanidine (mIBG).Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2021
    Article
  10. Review
  11. Characterization ofMolecular pharmacology · 2020
    Article
  12. Membrane Transporters in Human Parotid Gland-Targeted Proteomics Approach.International journal of molecular sciences · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David J WagnerDepartments of Pharmaceutics (D.J.W., L.M.S., D.D.S., J.W.) and Pharmacy (S.A.), University of Washington, Seattle, Washington.ORCID 0000-0002-5805-930X
Laura M ShiremanDepartments of Pharmaceutics (D.J.W., L.M.S., D.D.S., J.W.) and Pharmacy (S.A.), University of Washington, Seattle, Washington.
Sojung AhnDepartments of Pharmaceutics (D.J.W., L.M.S., D.D.S., J.W.) and Pharmacy (S.A.), University of Washington, Seattle, Washington.
Danny D ShenDepartments of Pharmaceutics (D.J.W., L.M.S., D.D.S., J.W.) and Pharmacy (S.A.), University of Washington, Seattle, Washington.
Joanne WangDepartments of Pharmaceutics (D.J.W., L.M.S., D.D.S., J.W.) and Pharmacy (S.A.), University of Washington, Seattle, Washington jowang@uw.edu.
University of Washington · US

Funding

Pharmacological Sciences SupplementT32GM007750 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 1985 to 2023
$12.6M
Understanding Fetal Exposure to Cannabinoids Through In Vitro and In Vivo StudiesP01DA032507 · NIDA · UNIVERSITY OF WASHINGTON · PI UNADKAT, JASHVANT D · 2013 to 2023
$12.4M
NIDA NIH HHS P01 DA032507NIGMS NIH HHS T32 GM007750
6 · The paper itself

Abstract

Methamphetamine is one of the most widely abused illicit drugs. Although human intoxication and multiple tissue toxicities frequently occur in abusers, little is known about the distribution of methamphetamine or its primary metabolites, amphetamine and

Indexed as

AnimalsBiological TransportHEK293 CellsHumansMaleMethamphetamineMiceMice, KnockoutMuscle, SkeletalOctamer Transcription Factor-3Salivary GlandsTissue DistributionMethamphetamineOctamer Transcription Factor-3Pou5f1 protein, mouse

Identifiers

PMID29915156
PMCPMC6081671
OpenAlexW2809054566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.