Evidence map›Paper›PMID 29915139›Full record

ArticleBiology open2018

Non-invasive assessment of liver disease in rats using multiparametric magnetic resonance imaging: a feasibility study.

Anna M Hoy, Natasha McDonald, Ross J Lennen, Matteo Milanesi, Amy H Herlihy, Timothy J Kendall, William Mungall, Michael Gyngell, Rajarshi Banerjee, Robert L Janiczek and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. No Sex Differences in the Amount of Type IV Collagen in Wistar Rats Regardless of Sampling Strategy.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. In Vivo Magnetic Resonance Spectroscopy of Hyperpolarized [1-Journal of magnetic resonance imaging : JMRI · 2021
    Article
  7. Article
  8. Article
  9. Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Anna M HoyMRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK.
Natasha McDonaldMRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK.
Ross J LennenBHF/University of Edinburgh Centre for Cardiovascular Science, Edinburgh EH16 4TJ, UK.
Matteo MilanesiPerspectum Diagnostics, Oxford OX1 2ET, UK.
Amy H HerlihyPerspectum Diagnostics, Oxford OX1 2ET, UK.
Timothy J KendallMRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK.
William MungallBiomedical Research Resources, University of Edinburgh, Edinburgh EH16 4SB, UK.
Michael GyngellPerspectum Diagnostics, Oxford OX1 2ET, UK.
Rajarshi BanerjeePerspectum Diagnostics, Oxford OX1 2ET, UK.
Robert L JaniczekGlaxoSmithKline (Experimental Medicine Imaging), Stevenage SG1 2NY, UK.
Philip S MurphyGlaxoSmithKline (Experimental Medicine Imaging), Stevenage SG1 2NY, UK.
Maurits A JansenBHF/University of Edinburgh Centre for Cardiovascular Science, Edinburgh EH16 4TJ, UK.
Jonathan A FallowfieldMRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK Jonathan.Fallowfield@ed.ac.uk.ORCID http://orcid.org/0000-0002-5741-1471
Centre for Inflammation Research · GBUniversity of Edinburgh · GBGlaxoSmithKline (United Kingdom) · GB

Funding

Chief Scientist Office SCD/20Wellcome Trust
6 · The paper itself

Abstract

Non-invasive quantitation of liver disease using multiparametric magnetic resonance imaging (MRI) could refine clinical care pathways, trial design and preclinical drug development. The aim of this study was to evaluate the use of multiparametric MRI in experimental models of liver disease. Liver injury was induced in rats using 4 or 12 weeks of carbon tetrachloride (CCl

Indexed as

Chronic liver diseaseMultiparametric MRIRat

Identifiers

PMID29915139
PMCPMC6078340
OpenAlexW2795938700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.