Evidence map›Paper›PMID 29915128›Full record

Trial reportDiabetes care2018

Long-term Outcomes of Lifestyle Intervention to Prevent Diabetes in American Indian and Alaska Native Communities: The Special Diabetes Program for Indians Diabetes Prevention Program.

Luohua Jiang, Ann Johnson, Katherine Pratte, Janette Beals, Ann Bullock, Spero M Manson, Special Diabetes Program for Indians Diabetes Prevention Program

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luohua JiangDepartment of Epidemiology, School of Medicine, University of California, Irvine, Irvine, CA lhjiang@uci.edu.ORCID 0000-0002-2281-7260
Ann JohnsonCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.
Katherine PratteCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.
Janette BealsCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.
Ann BullockDivision of Diabetes Treatment and Prevention, Indian Health Service, Rockville, MD.
Spero M MansonCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.
Special Diabetes Program for Indians Diabetes Prevention Program
Colorado School of Public Health · USIndian Health Service · USUniversity of California, Irvine · US

Funding

TRANSLATIONAL RESEARCH COREP30DK092923 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Angela Gwen Brega · 2011 to 2026
$10.2M
Comparative Effectiveness Evaluation of a Diabetes Case Management Intervention in AI/AN CommunitiesR21DK108187 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI JIANG, LUOHUA · 2016 to 2017
$425k
NIDDK NIH HHS P30 DK092923NIDDK NIH HHS R21 DK108187
6 · The paper itself

Abstract

objectiveEvidence for long-term translational effectiveness of lifestyle interventions in minority populations is scarce. This article reports long-term outcomes, for up to 10 years, of such an intervention to prevent diabetes in American Indian and Alaska Native (AI/AN) communities. RESEARCH DESIGN AND

methodsFrom January 2006 to July 2016, the Special Diabetes Program for Indians Diabetes Prevention Program implemented the Diabetes Prevention Program lifestyle intervention among 46 AI/AN health care programs. Enrolled participants underwent a thorough clinical assessment at baseline, after completing the Lifestyle Balance Curriculum (postcurriculum assessment), and annually thereafter. Proportional hazards regression was used to estimate the association between diabetes incidence and postcurriculum weight loss status.

resultsOf 8,652 enrolled participants, 65% finished the postcurriculum assessment. The assessment completion rate diminished over time to 13% in year 10. Among those with postcurriculum weight measurements, 2,028 (36%) lost >5% of their initial weight, 978 (17%) lost 3-5%, whereas 2,604 (47%) had <3% weight loss (average weight loss 3.8%). Compared with those with <3% weight loss, participants with >5% weight loss had a 64% (95% CI 54-72) lower risk of developing diabetes during the first 6 years of follow-up, whereas those with 3-5% weight loss had 40% (95% CI 24-53) lower risk.

conclusionsModerate to small weight loss was associated with substantially reduced long-term risk of diabetes in diverse AI/AN communities. High participant attrition rates and nonoptimal postcurriculum weight loss are important challenges found in this translational effort implemented in an underserved population.

Indexed as

American Indian or Alaska NativeDiabetes Mellitus, Type 2Life StylePrediabetic StateWeight Reduction ProgramsBody WeightDiet, ReducingFemaleHumansIncidenceMaleMiddle AgedRisk Reduction BehaviorTime FactorsWeight Loss

Identifiers

PMID29915128
PMCPMC6014547
OpenAlexW2808026512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.