Trial reportProceedings of the National Academy of Sciences of the United States of America2018
Lack of group-to-individual generalizability is a threat to human subjects research.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 364 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
364 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Social support and internalizing psychopathology among sexual and gender minority individuals: A meta-analysis.Clinical psychology review · 2026Pooled it
- Temperament, personality, and psychopathology in youth: A preregistered multilevel meta-analytic review and preregistered large-scale replication and extension.Psychological bulletin · 2026Pooled it
- Pooled it
- Within-person associations between psychological and contextual factors and lapse incidence in smokers attempting to quit: A systematic review and meta-analysis of ecological momentary assessment studies.Addiction (Abingdon, England) · 2023Pooled it
- Pooled it
- Voice Patterns as Markers of Schizophrenia: Building a Cumulative Generalizable Approach Via a Cross-Linguistic and Meta-analysis Based Investigation.Schizophrenia bulletin · 2023Pooled it
- Understanding health behaviours in context: A systematic review and meta-analysis of ecological momentary assessment studies of five key health behaviours.Health psychology review · 2022Pooled it
- A Systematic Review of Time Series Classification Techniques Used in Biomedical Applications.Sensors (Basel, Switzerland) · 2022Pooled it
- Evaluating the Let's Move It intervention programme theory for adolescents' physical activity: Theorized psychosocial mechanisms of behavioural changes.British journal of health psychology · 2025Trial
- PTSD symptom networks during treatment among residents in domestic violence shelters.Journal of counseling psychology · 2025Trial
- Electric Field Navigated 1-Hz rTMS for Poststroke Motor Recovery: The E-FIT Randomized Controlled Trial.Stroke · 2023Trial
- Episodic future thinking and compassion reduce non-compliance urges regarding public health guidelines: a randomised controlled trial.BMC public health · 2023Trial
- Walking improvement in chronic incomplete spinal cord injury with exoskeleton robotic training (WISE): a randomized controlled trial.Spinal cord · 2022Trial
- Digital Phenotyping of Lifestyle Profiles and Mental Well-Being in German Adults: Prospective Longitudinal Cohort Study.Journal of medical Internet research · 2026Article
- The power of friendships in adolescents' daily lives: Bi-directional within-person associations between friendship interaction quality and affect.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026Article
- Disentangling within- and between-subject correlations in cognitive models: The essential role of hierarchical estimation.Behavior research methods · 2026Article
- Seven challenges in affective inertia research.Emotion (Washington, D.C.) · 2026Review
- School Relational Environment and Adolescent Depressive Symptoms: Insights from Latent Profile and Network Analysis.Child psychiatry and human development · 2026Article
- Complex affect dynamics offer limited incremental value for cross-sectional prediction of psychological and behavioural variables in cross-validated models.BMC medicine · 2026Article
- Daily appearance-related safety behaviors are associated with same-day appearance concerns and social anxiety: a preliminary examination.Cognitive behaviour therapy · 2026Article
304 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Only for ergodic processes will inferences based on group-level data generalize to individual experience or behavior. Because human social and psychological processes typically have an individually variable and time-varying nature, they are unlikely to be ergodic. In this paper, six studies with a repeated-measure design were used for symmetric comparisons of interindividual and intraindividual variation. Our results delineate the potential scope and impact of nonergodic data in human subjects research. Analyses across six samples (with 87-94 participants and an equal number of assessments per participant) showed some degree of agreement in central tendency estimates (mean) between groups and individuals across constructs and data collection paradigms. However, the variance around the expected value was two to four times larger within individuals than within groups. This suggests that literatures in social and medical sciences may overestimate the accuracy of aggregated statistical estimates. This observation could have serious consequences for how we understand the consistency between group and individual correlations, and the generalizability of conclusions between domains. Researchers should explicitly test for equivalence of processes at the individual and group level across the social and medical sciences.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.