Evidence map›Paper›PMID 29915051›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Serine metabolism in the brain regulates starvation-induced sleep suppression in

Jun Young Sonn, Jongbin Lee, Min Kyung Sung, Hwajung Ri, Jung Kyoon Choi, Chunghun Lim, Joonho Choe

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jun Young SonnDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.
Jongbin LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.
Min Kyung SungDepartment of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.
Hwajung RiDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.
Jung Kyoon ChoiDepartment of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.
Chunghun LimSchool of Life Sciences, Ulsan National Institute of Science and Technology, 44919 Ulsan, Republic of Korea clim@unist.ac.kr jchoe@kaist.ac.kr.
Joonho ChoeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea; clim@unist.ac.kr jchoe@kaist.ac.kr.
Korea Advanced Institute of Science and Technology · KRKorea Institute of Brain Science · KRUlsan National Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep and metabolism are physiologically and behaviorally intertwined; however, the molecular basis for their interaction remains poorly understood. Here, we identified a serine metabolic pathway as a key mediator for starvation-induced sleep suppression. Transcriptome analyses revealed that enzymes involved in serine biosynthesis were induced upon starvation in

Indexed as

MutationSignal TransductionAnimalsBehavior, AnimalBrainDrosophila melanogasterDrosophila ProteinsL-Serine DehydrataseSerineStarvationDrosophila ProteinsL-Serine DehydrataseSerineserinesleep regulationstarvation

Identifiers

PMID29915051
PMCPMC6142195
OpenAlexW2808460871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.