Evidence map›Paper›PMID 29915046›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Crystal structures of a [NiFe] hydrogenase large subunit HyhL in an immature state in complex with a Ni chaperone HypA.

Sunghark Kwon, Satoshi Watanabe, Yuichi Nishitani, Takumi Kawashima, Tamotsu Kanai, Haruyuki Atomi, Kunio Miki

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. ATP-Triggered Fe(CN)Journal of the American Chemical Society · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Structure, function, and biosynthesis of nickel-dependent enzymes.Protein science : a publication of the Protein Society · 2020
    Review
  10. Article
  11. Article
  12. Review
  13. Microbe Profile:Microbiology (Reading, England) · 2019
    Article
  14. Bimodal Nickel-Binding Site onInorganic chemistry · 2019
    Article
  15. Article
  16. Article
  17. Structure and dynamics of Helicobacter pylori nickel-chaperone HypA: an integrated approach using NMR spectroscopy, functional assays and computational tools.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sunghark KwonDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, 606-8502 Kyoto, Japan.
Satoshi WatanabeInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Aoba-ku, 980-8577 Sendai, Japan.ORCID 0000-0002-1130-0477
Yuichi NishitaniDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, 606-8502 Kyoto, Japan.
Takumi KawashimaDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, 606-8502 Kyoto, Japan.
Tamotsu KanaiDepartment of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, 615-8510 Kyoto, Japan.
Haruyuki AtomiDepartment of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, 615-8510 Kyoto, Japan.
Kunio MikiDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, 606-8502 Kyoto, Japan; miki@kuchem.kyoto-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ni-Fe clusters are inserted into the large subunit of [NiFe] hydrogenases by maturation proteins such as the Ni chaperone HypA via an unknown mechanism. We determined crystal structures of an immature large subunit HyhL complexed with HypA from

Indexed as

Archaeal ProteinsCrystallography, X-RayHydrogenaseMolecular ChaperonesMultiprotein ComplexesProtein Structure, QuaternaryProtein SubunitsThermococcusArchaeal ProteinsHydrogenaseMolecular ChaperonesMultiprotein Complexesnickel-iron hydrogenaseProtein Subunitshydrogenase maturationHyhLHypANi insertionN-terminal binding mode

Identifiers

PMID29915046
PMCPMC6142260

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.