Evidence map›Paper›PMID 29915020›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Risk of Preeclampsia and Pregnancy Complications in Women With a History of Acute Kidney Injury.

Jessica Sheehan Tangren, Wan Ahmad Hafiz Wan Md Adnan, Camille E Powe, Jeffrey Ecker, Kate Bramham, Michelle A Hladunewich, Elizabeth Ankers, S Ananth Karumanchi, Ravi Thadhani

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. The pathophysiology of pre-eclampsia.Nature reviews. Nephrology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. The death of a myth: Females are not resistant to acute kidney injury.Clinical science (London, England : 1979) · 2025
    Article
  12. NephroCheck AKI risk scores (TIMP-2 and IGFBP7) in pregnancy.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 6 countries.

Jessica Sheehan TangrenFrom the Division of Nephrology, Department of Medicine (J.S.T., E.A., R.T.) jtangren@partners.org.
Wan Ahmad Hafiz Wan Md AdnanMassachusetts General Hospital, Boston; Nephrology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia (W.A.H.W.M.A.).
Camille E PoweDiabetes Unit, Division of Endocrinology, Department of Medicine (C.E.P.).
Jeffrey EckerDepartment of Obstetrics and Gynecology (J.E.).
Kate BramhamDepartment of Renal Medicine, King's College London and King's Health Partners, London, United Kingdom (K.B.).
Michelle A HladunewichMassachusetts General Hospital, Boston; Nephrology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia (W.A.H.W.M.A.).
Elizabeth AnkersFrom the Division of Nephrology, Department of Medicine (J.S.T., E.A., R.T.).
S Ananth KarumanchiDepartment of Medicine and Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical (S.A.K.).
Ravi ThadhaniFrom the Division of Nephrology, Department of Medicine (J.S.T., E.A., R.T.).
Harvard University · USDiabetes Australia · AUHadassah Medical Center · ILKings Health Partners · GBMassachusetts General Hospital · USUniversity of Malaya · MY

Funding

Elucidating Determinants of Gestational Beta-Cell Adaptation and FailureK23DK113218 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI POWE, CAMILLE ELISE · 2017 to 2021
$1.0M
Patient Oriented Studies of Vitamin D in Chronic Kidney DiseaseK24DK094872 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI THADHANI, RAVI · 2012 to 2016
$546k
NIDDK NIH HHS K23 DK113218NIDDK NIH HHS K24 DK094872
6 · The paper itself

Abstract

An episode of clinically recovered acute kidney injury (r-AKI) has been identified as a risk factor for future hypertension and cardiovascular disease. Our objective was to assess whether r-AKI was associated with future preeclampsia and other adverse pregnancy outcomes and to identify whether severity of AKI or time interval between AKI and pregnancy was associated with pregnancy complications. We conducted a retrospective cohort study of women who delivered infants between 1998 and 2016 at Massachusetts General Hospital. AKI was defined using the 2012 Kidney Disease Improving Global Outcomes laboratory criteria with subsequent clinical recovery (estimate glomerular filtration rate, >90 mL/min per 1.73 m

Indexed as

Acute Kidney InjuryAdultFemaleFollow-Up StudiesGestational AgeGlomerular Filtration RateHumansIncidenceInfant, NewbornMassachusettsPre-EclampsiaPregnancyPregnancy ComplicationsPregnancy OutcomeRetrospective StudiesRisk Assessmentacute kidney injuryepidemiologyhypertensionpreeclampsiapregnancy

Identifiers

PMID29915020
PMCPMC6074052
OpenAlexW2892249124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.