Evidence map›Paper›PMID 29915013›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Bradykinin Stimulates Renal Na

Dan-Dan Zhang, Zhong-Xiuzi Gao, Carlos P Vio, Yu Xiao, Peng Wu, Hao Zhang, Xi-Wen Guo, Xin-Xin Meng, Li Gu, Jun-Lin Wang and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Inwardly rectifying KAmerican journal of physiology. Cell physiology · 2022
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  17. Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal KAmerican journal of physiology. Renal physiology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Dan-Dan ZhangFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Zhong-Xiuzi GaoDepartment of Pharmacology, New York Medical College, Valhalla (Z.-X.G., P.W., D.-H.L., W.-H.W.).
Carlos P VioDepartment of Physiology, Center for Aging and Regeneration Care-UC, Pontificia Universidad Catolica de Chile, Santiago (C.P.V.).
Yu XiaoFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Peng WuDepartment of Pharmacology, New York Medical College, Valhalla (Z.-X.G., P.W., D.-H.L., W.-H.W.).
Hao ZhangFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Xi-Wen GuoFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Xin-Xin MengFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Li GuFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Jun-Lin WangFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Xin-Peng DuanFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.).
Dao-Hong LinDepartment of Pharmacology, New York Medical College, Valhalla (Z.-X.G., P.W., D.-H.L., W.-H.W.).
Wen-Hui WangDepartment of Pharmacology, New York Medical College, Valhalla (Z.-X.G., P.W., D.-H.L., W.-H.W.).
Ruimin GuFrom the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.) ruimingu2916@163.com wenhui_wang@nymc.edu.
Harbin Medical University · CNNew York Medical College · US

Funding

Role of Kir4.1 in Regulating NCC and ROMK in DCTR01DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2001 to 2020
$7.4M
Kir5.1 regulates Kir4.1 ubiquitination by Nedd4-2 in DCTR01DK115366 · NIDDK · NEW YORK MEDICAL COLLEGE · PI LIN, DAO-HONG · 2018 to 2021
$1.5M
Role of Kir4.1 in Regulating NCC and ROMK in DCTR56DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2021 to 2021
$100k
NIDDK NIH HHS R01 DK054983NIDDK NIH HHS R01 DK115366NIDDK NIH HHS R56 DK054983
6 · The paper itself

Abstract

Stimulation of BK2R (bradykinin [BK] B2 receptor) has been shown to increase renal Na

Indexed as

AnimalsBradykininFemaleImmunohistochemistryIon TransportKidney Tubules, DistalMaleMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutModels, AnimalNatriuresisPatch-Clamp TechniquesPotassium Channels, Inwardly RectifyingSodiumBradykininPotassium Channels, Inwardly RectifyingSodiumSolute Carrier Family 12, Member 3bradykinin B2, receptordiureticshypertensionion transportsodium-chloride symporter

Identifiers

PMID29915013
PMCPMC6043363
OpenAlexW2808024378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.