Evidence map›Paper›PMID 29914966›Full record

ArticleAntimicrobial agents and chemotherapy2018

Colistin Heteroresistance and Involvement of the PmrAB Regulatory System in Acinetobacter baumannii.

Yannick Charretier, Seydina M Diene, Damien Baud, Sonia Chatellier, Emmanuelle Santiago-Allexant, Alex van Belkum, Ghislaine Guigon, Jacques Schrenzel

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Molecular Characterization of Colistin-Resistant ClinicalAntibiotics (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. A Clinically Silent Resistance Phenotype That PromotesbioRxiv : the preprint server for biology · 2026
    Article
  8. Resistance, heteroresistance, and fitness costs drive colistin treatment failure duringProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. PmrAB, the two-component system ofJournal of bacteriology · 2024
    Article
  15. Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Heteroresistance to Colistin in Clinical Isolates ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Yannick CharretierGenomic Research Laboratory, Service of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland yannick.charretier@genomic.ch.ORCID 0000-0002-8772-0697
Seydina M DieneGenomic Research Laboratory, Service of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Damien BaudGenomic Research Laboratory, Service of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Sonia ChatellierInnovation Unit, bioMérieux SA, La Balme Les Grottes, France.
Emmanuelle Santiago-AllexantInnovation Unit, bioMérieux SA, Marcy l'Etoile, France.
Alex van BelkumData Analytics Unit, bioMérieux SA, La Balme Les Grottes, France.
Ghislaine GuigonInnovation Unit, bioMérieux SA, Marcy l'Etoile, France.
Jacques SchrenzelGenomic Research Laboratory, Service of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Institut Mérieux (France) · FRUniversity Hospital of Geneva · CHbioMérieux (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug-resistant

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsBase SequenceColistinDrug Resistance, BacterialHumansMicrobial Sensitivity TestsPolymorphism, Single NucleotideSequence Analysis, DNATranscription FactorsAnti-Bacterial AgentsBacterial ProteinsColistinpmrA protein, BacteriaPmrB protein, bacteriaTranscription FactorsAcinetobactercolistinheteroresistancePmrAB

Identifiers

PMID29914966
PMCPMC6125516
OpenAlexW2951589579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.