Evidence map›Paper›PMID 29914953›Full record

ArticleAntimicrobial agents and chemotherapy2018

Genes and Proteins Involved in

Rubén Monárrez, Yin Wang, Yingmei Fu, Chun-Hsing Liao, Ryo Okumura, Molly R Braun, George A Jacoby, David C Hooper

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Journal of bacteriology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Overexpression ofInternational journal of microbiology · 2021
    Article
  8. Cold shock induces chromosomalAntimicrobial agents and chemotherapy · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Rubén MonárrezDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Yin WangDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Yingmei FuDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Chun-Hsing LiaoDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Ryo OkumuraDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Molly R BraunDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
George A JacobyLahey Hospital and Medical Center, Burlington, Massachusetts, USA.
David C HooperDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA dhooper@mgh.harvard.edu.
Harvard University · USHarbin Medical University · CNLahey Medical Center · USMassachusetts General Hospital · US

Funding

Plasmid-mediated Quinolone ResistanceR01AI057576 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HOOPER, DAVID C · 2004 to 2018
$5.3M
NIAID NIH HHS R01 AI057576
6 · The paper itself

Abstract

Expression of the quinolone resistance gene

Indexed as

Anti-Bacterial AgentsBacterial ProteinsCiprofloxacinDNA-Binding ProteinsDNA GyraseEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialIntegration Host FactorsIntracellular Signaling Peptides and ProteinsLac OperonPlasmidsAnti-Bacterial AgentsBacterial ProteinsCiprofloxacinDnaA protein, BacteriaDNA-Binding ProteinsDNA GyraseEscherichia coli Proteinsintegration host factor, E coliIntegration Host FactorsIntracellular Signaling Peptides and ProteinsQnr protein, E coliqnrS1 protein, E coliantibiotic resistanceplasmid-mediated resistancequinolones

Identifiers

PMID29914953
PMCPMC6125508
OpenAlexW2809340773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.