Evidence map›Paper›PMID 29914952›Full record

ArticleAntimicrobial agents and chemotherapy2018

Contribution of Novel Amino Acid Alterations in PmrA or PmrB to Colistin Resistance in

Toyotaka Sato, Tsukasa Shiraishi, Yoshiki Hiyama, Hiroyuki Honda, Masaaki Shinagawa, Masaru Usui, Koji Kuronuma, Naoya Masumori, Satoshi Takahashi, Yutaka Tamura and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Antibiotic Resistance during COVID-19: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
  3. Review
  4. Article
  5. The fatty acid synthesis geneMicrobiology spectrum · 2025
    Article
  6. Detection of plasmid-mediatedInfectious diseases & immunity · 2025
    Article
  7. Article
  8. Article
  9. Trends of Colistin MIC AmongJournal of tropical medicine · 2025
    Article
  10. Article
  11. Mobile Colistin-Resistant GenesAntibiotics (Basel, Switzerland) · 2024
    Article
  12. Upregulation ofNew microbes and new infections · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Polymyxins: recent advances and challenges.Frontiers in pharmacology · 2024
    Review
  17. Article
  18. Genomic Evidence ofMicrobiology spectrum · 2023
    Article
  19. Identification ofAntibiotics (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Toyotaka SatoDepartment of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan sato.t@sapmed.ac.jp.
Tsukasa ShiraishiDepartment of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Yoshiki HiyamaDepartment of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Hiroyuki HondaDepartment of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Masaaki ShinagawaDivision of Laboratory Medicine, Sapporo Medical University Hospital, Sapporo, Japan.
Masaru UsuiLaboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.
Koji KuronumaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Naoya MasumoriDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Satoshi TakahashiDivision of Laboratory Medicine, Sapporo Medical University Hospital, Sapporo, Japan.
Yutaka TamuraLaboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.
Shin-Ichi YokotaDepartment of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Sapporo Medical University · JPRakuno Gakuen University · JPSapporo Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin is a last-line drug for multidrug-resistant Gram-negative bacteria. We previously reported four plasmid-mediated colistin resistance (

Indexed as

Amino Acid SubstitutionAnti-Bacterial AgentsBacterial ProteinsColistinDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli ProteinsHexosyltransferasesHumansLipid AMicrobial Sensitivity TestsSequence DeletionTranscription FactorsAnti-Bacterial AgentsBacterial ProteinsColistinEscherichia coli ProteinsHexosyltransferasesL-Ara4N transferaseLipid AMCR-1 protein, E colipmrA protein, BacteriaPmrB protein, bacteriaTranscription Factorsantimicrobial resistancebacterial infectionEscherichia colilipid APmrAB

Identifiers

PMID29914952
PMCPMC6125499
OpenAlexW2807967482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.