Evidence map›Paper›PMID 29914949›Full record

ArticleAntimicrobial agents and chemotherapy2018

Pharmacokinetics of Tedizolid in Plasma and Sputum of Adults with Cystic Fibrosis.

A Young J Park, Joshua Wang, Jordanna Jayne, Lynn Fukushima, Adupa P Rao, David Z D'Argenio, Paul M Beringer

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Next-generation rifamycins for the treatment of mycobacterial infections.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Importance and Reality of TDM for Antibiotics Not Covered by Insurance in Japan.International journal of environmental research and public health · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

A Young J ParkDepartment of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California, USA.
Joshua WangDepartment of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California, USA.
Jordanna JayneDepartment of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California, USA.
Lynn FukushimaDivision of Pulmonary and Critical Care Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Adupa P RaoDivision of Pulmonary and Critical Care Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
David Z D'ArgenioBiomedical Simulations Resource, Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.
Paul M BeringerDepartment of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California, USA beringer@usc.edu.
University of Southern California · US

Funding

TrainingP41EB001978 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KHOO, MICHAEL C K · 2003 to 2017
$18.1M
NIBIB NIH HHS P41 EB001978
6 · The paper itself

Abstract

Over the past decade, the prevalence of infections involving methicillin-resistant

Indexed as

Administration, IntravenousAdministration, OralAdultAnti-Bacterial AgentsBiological AvailabilityCross-Over StudiesCystic FibrosisFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusOrganophosphatesOxazolesPlasmaProspective StudiesSputumAnti-Bacterial AgentsOrganophosphatesOxazolestedizolid phosphatecystic fibrosispharmacokineticstedizolid

Identifiers

PMID29914949
PMCPMC6125567
OpenAlexW2808254273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.