Evidence map›Paper›PMID 29914939›Full record

ArticleDisease models & mechanisms2018

Transcriptional upregulation of

Elliot J Jokl, Gideon L Hughes, Tobias Cracknell, Mary E Pownall, Gonzalo Blanco

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elliot J JoklDepartment of Biology, University of York, Wentworth Way, York YO10 5DD, UK.ORCID 0000-0003-2556-3777
Gideon L HughesDepartment of Biology, University of York, Wentworth Way, York YO10 5DD, UK.ORCID 0000-0001-8047-8888
Tobias CracknellDepartment of Biology, University of York, Wentworth Way, York YO10 5DD, UK.ORCID 0000-0003-0622-5932
Mary E PownallDepartment of Biology, University of York, Wentworth Way, York YO10 5DD, UK.ORCID 0000-0003-2329-5844
Gonzalo BlancoDepartment of Biology, University of York, Wentworth Way, York YO10 5DD, UK gonzalo.blanco@york.ac.uk.ORCID 0000-0003-3827-3111
University of York · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J014443/1Wellcome TrustWellcome Trust 204829
6 · The paper itself

Abstract

The importance of kyphoscoliosis peptidase (KY) in skeletal muscle physiology has recently been emphasised by the identification of novel human myopathies associated with KY deficiency. Neither the pathogenic mechanism of KY deficiency nor a specific role for KY in muscle function have been established. However, aberrant localisation of filamin C (FLNC) in muscle fibres has been shown in humans and mice with loss-of-function mutations in the

Indexed as

AutophagyAdaptor Proteins, Signal TransducingAnimalsApoptosis Regulatory ProteinsBase SequenceCell DifferentiationCell LineCRISPR-Cas SystemsDisease Models, AnimalFilaminsGene EditingMechanotransduction, CellularMice, KnockoutMuscle Fibers, SkeletalMuscle ProteinsMuscular DiseasesAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsBag3 protein, mouseBAG3 protein, zebrafishFilaminsKY protein, mouseKY protein, zebrafishMuscle ProteinsPeptide HydrolasesZebrafish ProteinsBAG3Chaperone-assisted selective autophagyFLNCKyphoscoliosis peptidaseMyopathy

Identifiers

PMID29914939
PMCPMC6078408
OpenAlexW2808254828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.