Evidence map›Paper›PMID 29914645›Full record

ArticleBiophysical journal2018

Macrodiscs Comprising SMALPs for Oriented Sample Solid-State NMR Spectroscopy of Membrane Proteins.

Jasmina Radoicic, Sang Ho Park, Stanley J Opella

Abstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
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  5. The journal of physical chemistry. B · 2024
    Review
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  7. Article
  8. Article
  9. Article
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  13. Article
  14. Article
  15. Synthesis, Characterization, and Nanodisc Formation of Non-ionic Polymers*.Angewandte Chemie (International ed. in English) · 2021
    Article
  16. Solid-State NMR Study to Probe the Effects of Divalent Metal Ions (CaLangmuir : the ACS journal of surfaces and colloids · 2021
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jasmina RadoicicDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California.
Sang Ho ParkDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California.
Stanley J OpellaDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California. Electronic address: sopella@ucsd.edu.

Funding

RESOURCE FOR SOLID STATE NMR OF PROTEINSP41EB002031 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OPELLA, STANLEY J · 2003 to 2018
$16.3M
Structures, Dynamics, and Functions of Membrane ProteinsR35GM122501 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OPELLA, STANLEY J · 2017 to 2021
$2.5M
NIBIB NIH HHS P41 EB002031NIGMS NIH HHS R35 GM122501
6 · The paper itself

Abstract

Macrodiscs, which are magnetically alignable lipid bilayer discs with diameters of >30 nm, were obtained by solubilizing protein-containing liposomes with styrene-maleic acid copolymers. Macrodiscs provide a detergent-free phospholipid bilayer environment for biophysical and functional studies of membrane proteins under physiological conditions. The narrow resonance linewidths observed from membrane proteins in styrene-maleic acid macrodiscs advance structure determination by oriented sample solid-state NMR spectroscopy.

Indexed as

Nuclear Magnetic Resonance, BiomolecularLipid BilayersMagnetsMaleatesMembrane ProteinsStyreneLipid BilayersMaleatesmaleic acidMembrane ProteinsStyrene

Identifiers

PMID29914645
PMCPMC6035293

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.