Evidence map›Paper›PMID 29914351›Full record

ArticleBMC genomics2018

Single-strand DNA processing: phylogenomics and sequence diversity of a superfamily of potential prokaryotic HuH endonucleases.

Yves Quentin, Patricia Siguier, Mick Chandler, Gwennaele Fichant

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yves QuentinLaboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Centre National de la Recherche Scientifique (CNRS), Université de Toulouse, UPS, F-31062, Toulouse, France. Yves.Quentin@ibcg.biotoul.fr.ORCID http://orcid.org/0000-0001-8248-0586
Patricia SiguierLaboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Centre National de la Recherche Scientifique (CNRS), Université de Toulouse, UPS, F-31062, Toulouse, France.
Mick ChandlerLaboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Centre National de la Recherche Scientifique (CNRS), Université de Toulouse, UPS, F-31062, Toulouse, France. Mike.Chandler@ibcg.biotoul.fr.
Gwennaele FichantLaboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Centre National de la Recherche Scientifique (CNRS), Université de Toulouse, UPS, F-31062, Toulouse, France.
Centre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR‑12‑BSV8‑0009‑01
6 · The paper itself

Abstract

backgroundSome mobile genetic elements target the lagging strand template during DNA replication. Bacterial examples are insertion sequences IS608 and ISDra2 (IS200/IS605 family members). They use obligatory single-stranded circular DNA intermediates for excision and insertion and encode a transposase, TnpA

resultsA genome-wide analysis of sequences similar to TnpA

conclusionsWe established a detailed classification of TnpA

Indexed as

Amino Acid MotifsArchaeal ProteinsBacterial ProteinsDNA, Single-StrandedEndodeoxyribonucleasesGenetic VariationInverted Repeat SequencesMultigene FamilyPhylogenyProtein DomainsTransposasesArchaeal ProteinsBacterial ProteinsDNA, Single-StrandedEndodeoxyribonucleasesTransposasesHuH superfamilyInsertion sequenceRAYT/TnpAREPReplication forkREP sequencesTransposition

Identifiers

PMID29914351
PMCPMC6006769
OpenAlexW2949879400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.