Evidence map›Paper›PMID 29914215›Full record

ReviewInternational journal of molecular sciences2018

Role of MicroRNAs in Renal Parenchymal Diseases-A New Dimension.

Saeed Kamran Shaffi, David Galas, Alton Etheridge, Christos Argyropoulos

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  9. Journal of Cancer · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Saeed Kamran ShaffiDepartment of Internal Medicine, Division of Nephrology, University of New Mexico, Albuquerque, NM 87131, USA. kshaffi@salud.unm.edu.
David GalasPacific Northwest Research Institute, Seattle, WA 98122, USA. dgalas@pnri.org.
Alton EtheridgePacific Northwest Research Institute, Seattle, WA 98122, USA. aetheridge@pnri.org.
Christos ArgyropoulosDepartment of Internal Medicine, Division of Nephrology, University of New Mexico, Albuquerque, NM 87131, USA. cargyropoulos@sauld.unm.edu.
Pacific Northwest Diabetes Research Institute · USUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since their discovery in 1993, numerous microRNAs (miRNAs) have been identified in humans and other eukaryotic organisms, and their role as key regulators of gene expression is still being elucidated. It is now known that miRNAs not only play a central role in the processes that ensure normal development and physiology, but they are often dysregulated in various diseases. In this review, we present an overview of the role of miRNAs in normal renal development and physiology, in maladaptive renal repair after injury, and in the pathogenesis of renal parenchymal diseases. In addition, we describe methods used for their detection and their potential as therapeutic targets. Continued research on renal miRNAs will undoubtedly improve our understanding of diseases affecting the kidneys and may also lead to new therapeutic agents.

Indexed as

AnimalsHumansKidneyKidney DiseasesMicroRNAsMolecular Targeted TherapyRNAi TherapeuticsMicroRNAsmicro RNAmiRNAmiRNA-based therapeuticsmiRNA detectionmiRNA in renal parenchymal Diseasesrenal parenchymal diseases

Identifiers

PMID29914215
PMCPMC6032378
OpenAlexW2791874076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.