Evidence map›Paper›PMID 29914198›Full record

ArticleInternational journal of environmental research and public health2018

Seasonal Variations in Water-Quality, Antibiotic Residues, Resistant Bacteria and Antibiotic Resistance Genes of

Vishal Diwan, Nada Hanna, Manju Purohit, Salesh Chandran, Emilia Riggi, Vivek Parashar, Ashok J Tamhankar, Cecilia Stålsby Lundborg

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Persistence of Antibiotic-ResistantAntibiotics (Basel, Switzerland) · 2022
    Article
  11. Prevalence and Diversity of Antibiotic ResistantFrontiers in public health · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Extended Spectrum Beta-LactamaseTropical medicine and infectious disease · 2021
    Article
  16. Review
  17. Monitoring of Water Quality, Antibiotic Residues, and Antibiotic-ResistantInternational journal of environmental research and public health · 2020
    Article
  18. Article
  19. Antibiotic Resistance in Minimally Human-Impacted Environments.International journal of environmental research and public health · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Vishal DiwanDepartment of Public Health and Environment, R.D. Gardi Medical College, Ujjain 456006, India. vishal.diwan@ki.se.
Nada HannaDepartment of Public Health Sciences, Global Health, Health Systems and Policy (HSP): Medicines Focusing Antibiotics, Karolinska Institutet, Stockholm 171 77, Sweden. nada.hanna@ki.se.
Manju PurohitDepartment of Public Health Sciences, Global Health, Health Systems and Policy (HSP): Medicines Focusing Antibiotics, Karolinska Institutet, Stockholm 171 77, Sweden. manju.purohit@ki.se.
Salesh ChandranHLL Biotech Ltd., Integrated Vaccines Complex, Melaripakkam (Post), Thirukalukundram Taluk, Chengalpattu 603001, India. saleshp@gmail.com.
Emilia RiggiDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia 27100, Italy. emilia.riggi01@ateneopv.it.
Vivek ParasharDepartment of Public Health and Environment, R.D. Gardi Medical College, Ujjain 456006, India. vivek.p@rdgmc.edu.in.
Ashok J TamhankarDepartment of Public Health Sciences, Global Health, Health Systems and Policy (HSP): Medicines Focusing Antibiotics, Karolinska Institutet, Stockholm 171 77, Sweden. ejetee@gmail.com.ORCID 0000-0003-0731-1680
Cecilia Stålsby LundborgDepartment of Public Health Sciences, Global Health, Health Systems and Policy (HSP): Medicines Focusing Antibiotics, Karolinska Institutet, Stockholm 171 77, Sweden. Cecilia.Stalsby.Lundborg@ki.se.ORCID 0000-0001-6525-1861
Karolinska Institutet · SEBiotech Park · INRuxmaniben Deepchand Gardi Medical College · INUniversity of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo characterize the seasonal variation, over one year, in water-quality, antibiotic residue levels, antibiotic resistance genes and antibiotic resistance in

methodsWater and sediment samples were collected from seven selected points from the Kshipra River in the Indian city of Ujjain in the summer, rainy season, autumn and winter seasons in 2014. Water quality parameters (physical, chemical and microbiological) were analyzed using standard methods. High-performance liquid chromatography⁻tandem mass spectrometry was used to determine the concentrations of antibiotic residues. In river water and sediment samples, antibiotic resistance and multidrug resistance patterns of isolated

resultsIn river water, seasonal variation was significantly associated with various water quality parameters, presence of sulfamethoxazole residues, bacteria resistant to ampicillin, cefepime, meropenem, amikacin, gentamicin, tigecycline, multidrug resistance and CTX-M-1 gene. The majority of the Extended Spectrum Beta-Lactamase (ESBL)-producing

conclusionsAntibiotic pollution, resistance and resistance genes in the Kshipra River showed significant seasonal variation. Guidelines and regulatory standards are needed to control environmental dissemination of these “pollutants” in this holy river.

Indexed as

SeasonsWater QualityAnti-Bacterial AgentsDrug ResiduesDrug Resistance, BacterialEnvironmental MonitoringEscherichia coliGeologic SedimentsIndiaRiversWater PollutantsAnti-Bacterial AgentsWater Pollutantsantibiotic residuesantibiotic resistanceantibiotic resistance genesIndiaKshipra Riverseasonal variation

Identifiers

PMID29914198
PMCPMC6024939
OpenAlexW2808613963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.