Evidence map›Paper›PMID 29914120›Full record

ArticleMolecules (Basel, Switzerland)2018

Pyridine-Ureas as Potential Anticancer Agents: Synthesis and In Vitro Biological Evaluation.

Mohamed El-Naggar, Hadia Almahli, Hany S Ibrahim, Wagdy M Eldehna, Hatem A Abdel-Aziz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Design, synthesis,Heliyon · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Pyridine C(spBeilstein journal of organic chemistry · 2023
    Review
  14. Phytochemistry and Anticancer Effects of Mangrove (Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Mohamed El-NaggarChemistry Department, Faculty of Sciences, University of Sharjah, Sharjah 27272, UAE. m5elnaggar@yahoo.com.
Hadia AlmahliDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. hadia.almahli@yahoo.com.
Hany S IbrahimDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 11829, Egypt. hany.s.ibrahim@gmail.com.ORCID 0000-0002-1048-4059
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. wagdy2000@gmail.com.
Hatem A Abdel-AzizDepartment of Applied Organic Chemistry, National Research Center, Dokki, Cairo 12622, Egypt. hatem_741@yahoo.com.
Egyptian Russian University · EGKafrelsheikh University · EGNational Research Centre · EGUniversity of Oxford · GBUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our endeavor towards the development of effective anticancer agents, a novel series of pyridine-ureas

Indexed as

Antineoplastic AgentsBreast NeoplasmsCell ProliferationCell SurvivalDrug Screening Assays, AntitumorFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsMolecular StructureProtein Kinase InhibitorsPyridinesUreaVascular Endothelial Growth Factor Receptor-2Antineoplastic AgentsKDR protein, humanProtein Kinase InhibitorsPyridinesUreaVascular Endothelial Growth Factor Receptor-2ADMEanticancerbreast cancerpyridine-ureasynthesisVEGFR-2

Identifiers

PMID29914120
PMCPMC6100082
OpenAlexW2808223966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.