Evidence map›Paper›PMID 29913263›Full record

ArticleThe journal of allergy and clinical immunology. In practice2019

Anaphylaxis after vaccination in a pediatric patient: further implicating alpha-gal allergy.

Cosby A Stone, Scott P Commins, Shailesh Choudhary, Chandra Vethody, Jill L Heavrin, Jared Wingerter, Jonathan A Hemler, Kenneth Babe, Elizabeth J Phillips, Allison E Norton

Abstract readCase ReportsLetter
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Cutaneous reactions to vaccination.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Anaphylaxis to Excipients in Current Clinical Practice: Evaluation and Management.Immunology and allergy clinics of North America · 2022
    Review
  11. [Alpha-gal syndrome : Overview of clinical presentation and pathophysiology].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  12. Review
  13. New Challenges in Drug Allergy: the Resurgence of Excipients.Current treatment options in allergy · 2022
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Tolerance of porcine pancreatic enzymes despite positive skin testing in alpha-gal allergy.The journal of allergy and clinical immunology. In practice · 2020
    Article
  19. Article
  20. Diagnosis and Management of Patients with the α-Gal Syndrome.The journal of allergy and clinical immunology. In practice · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cosby A StoneDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address: cosby.a.stone@vanderbilt.edu.
Scott P ComminsDivision of Allergy, Immunology and Rheumatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.
Shailesh ChoudharyDivision of Allergy, Immunology and Rheumatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.
Chandra VethodyDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn; Department of Medicine, University of Louisville School of Medicine, Louisville, Ky.
Jill L HeavrinDepartment of Emergency Medicine, Sumner Regional Medical Center, Gallatin, Tenn.
Jared WingerterDepartment of Emergency Medicine, Sumner Regional Medical Center, Gallatin, Tenn.
Jonathan A HemlerDivision of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tenn.
Kenneth BabeDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Elizabeth J PhillipsDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tenn; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tenn; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Allison E NortonDivision of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tenn.

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Understanding and preventing HLA-associated drug reactionsP50GM115305 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2015 to 2019
$13.0M
Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
Understanding alpha-gal red meat allergyR01AI135049 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott Palmer Commins · 2018 to 2026
$5.1M
The Structural and Functional Basis of HLA-associated Drug HypersensitivityR01AI103348 · NIAID · UNIVERSITY OF FLORIDA · PI OSTROV, DAVID A · 2013 to 2016
$1.5M
IgE to carbohydrates causes delayed anaphylaxisK08AI085190 · NIAID · UNIVERSITY OF VIRGINIA · PI COMMINS, SCOTT PALMER · 2010 to 2014
$651k
Single Cell definition of pathogenic T cells in Drug-induced Stevens-Johnson-Syndrome/Toxic epidermal necrolysisR21AI139021 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2018 to 2019
$435k
Delayed anaphylaxis to beef and pork: mechanisms and causes of a new food allergyR21AI087985 · NIAID · UNIVERSITY OF VIRGINIA · PI COMMINS, SCOTT PALMER, PLATTS-MILLS, THOMAS A. · 2010 to 2011
$422k
Delayed Anaphylaxis to Mammalian Meat caused by IgE Ab to alpha-galR56AI113095 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COMMINS, SCOTT PALMER · 2014 to 2014
$390k
NHLBI NIH HHS T32 HL087738NIAID NIH HHS K08 AI085190NIAID NIH HHS P30 AI110527NIAID NIH HHS R01 AI103348NIAID NIH HHS R01 AI135049NIAID NIH HHS R21 AI087985NIAID NIH HHS R21 AI139021NIAID NIH HHS R56 AI113095NIGMS NIH HHS P50 GM115305
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllergensAnaphylaxisAngioedemaAnimalsCattleChickenpox VaccineChild, PreschoolDyspneaFood HypersensitivityGelatinHumansImmunoglobulin EMaleMass VaccinationMeasles-Mumps-Rubella VaccineSkin TestsAllergensChickenpox VaccineGelatinImmunoglobulin EMeasles-Mumps-Rubella Vaccine

Identifiers

PMID29913263
PMCPMC6295282

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.