Evidence map›Paper›PMID 29913044›Full record

ReviewXenotransplantation2018

Accommodation in ABO-incompatible organ transplants.

Mayara Garcia de Mattos Barbosa, Marilia Cascalho, Jeffrey L Platt

Open access · bronzeAbstract readReview
In one paragraph

Review in Xenotransplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Antibody-mediated rejection in ABO-incompatible kidney transplantation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. B cells in transplant tolerance and rejection: friends or foes?Transplant international : official journal of the European Society for Organ Transplantation · 2020
    Review
  17. The five dimensions of B cell tolerance.Immunological reviews · 2019
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mayara Garcia de Mattos BarbosaDepartment of Surgery, University of Michigan, Ann Arbor, MI, USA.
Marilia CascalhoDepartment of Surgery, University of Michigan, Ann Arbor, MI, USA.
Jeffrey L PlattDepartment of Surgery, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-4915-0419
University of Michigan · US

Funding

Hepatocyte xenografts for treatment of acute liver failureR01AI122369 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FOX, IRA J., PLATT, JEFFREY L · 2016 to 2020
$5.0M
Immunodeficient Pigs for Stem Cell­-Based Regenerative MedicineR01OD023138 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI PIEDRAHITA, JORGE A · 2017 to 2020
$1.8M
Accommodation in TransplantationR56AI123262 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CASCALHO, MARILIA ISABEL, PLATT, JEFFREY L · 2016 to 2016
$388k
NIAID NIH HHS R01 AI122369NIAID NIH HHS R56 AI123262NIH HHS R01 OD023138
6 · The paper itself

Abstract

Accommodation refers to a condition in which a transplant (or any tissue) appears to resist immune-mediated injury and loss of function. Accommodation was discovered and has been explored most thoroughly in ABO-incompatible kidney transplantation. In this setting, kidney transplants bearing blood group A or B antigens often are found to function normally in recipients who lack and hence produce antibodies directed against the corresponding antigens. Whether accommodation is owed to changes in anti-blood group antibodies, changes in antigen or a change in the response of the transplant to antibody binding are critically reviewed and a new working model that allows for the kinetics of development of accommodation is put forth. Regardless of how accommodation develops, observations on the fate of ABO-incompatible transplants offer lessons applicable more broadly in transplantation and in other fields.

Indexed as

Kidney TransplantationTransplantation, HeterologousAnimalsGraft RejectionGraft SurvivalHumansTransplantation, HomologousTransplantsABO-incompatible transplantaccommodationblood groupblood typekidney transplantrejection

Identifiers

PMID29913044
PMCPMC6047762
OpenAlexW2808935368

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.