ArticlePloS one2018
Prevalence of antibiotic resistance in commensal Escherichia coli among the children in rural hill communities of Northeast India.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings.Scientific reports · 2021Pooled it
- Prevalence of multidrug-, extensive drug-, and pandrug-resistant commensalGlobal health action · 2019Pooled it
- Contributions and Challenges of High Throughput qPCR for Determining Antimicrobial Resistance in the Environment: A Critical Review.Molecules (Basel, Switzerland) · 2019Pooled it
- Public knowledge and attitude toward antibiotic use and antimicrobial resistance in Riyadh region.Journal of family medicine and primary care · 2026Article
- Susceptibility Profile and Multiple Antibiotics Resistance ofAntibiotics (Basel, Switzerland) · 2026Article
- Fluoroquinolone Resistance Patterns in Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2026Article
- Epidemiological insights into virulence and antimicrobial resistance ofFrontiers in veterinary science · 2026Article
- Investigating theRSC advances · 2025Article
- Antibiotic resistance profiles ofOpen veterinary journal · 2025Article
- Prevalence, antimicrobial resistance and biofilm forming ability ofFrontiers in veterinary science · 2025Article
- Biofabrication of copper oxide nanoparticles using Dalbergia sisso leaf extract for antibacterial, antibiofilm and antioxidant activities.Scientific reports · 2024Article
- Antimicrobial Resistance Surveillance in Human Pathogens in Ahmedabad: A One-Year Prospective Study.Indian journal of microbiology · 2024Article
- Genetic characterization of multidrug-resistantFrontiers in cellular and infection microbiology · 2024Article
- Antioxidant and Antimicrobial Evaluations ofMolecules (Basel, Switzerland) · 2023Article
- Prevalence of antimicrobial resistance in urine, blood, and wound pathogens among rural patients in Karnataka, India.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Reduced susceptibility to carbapenems inThe Pan African medical journal · 2023Article
- Large-Scale Studies on Antimicrobial Resistance and Molecular Characterization of Escherichia coli from Food Animals in Developed Areas of Eastern China.Microbiology spectrum · 2022Article
- Evidence of Community-Wide Spread of Multi-Drug ResistantMicroorganisms · 2022Article
- The Resistance Patterns inTropical medicine and infectious disease · 2022Article
- High Prevalence ofInfection & chemotherapy · 2022Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Commensal bacteria are the representative of the reservoir of antibiotic resistance genes present in a community. The usage of antibiotics along with the demographic factors is generally associated with an increase in antibiotics resistance in pathogens. Northeast (NE) India is untapped with regard to antibiotic resistance prevalence and spread. In the current study, the prevalence of antibiotic-resistant commensal Escherichia coli in pre-school and school-going children (n = 550, 1-14 years old) from the rural areas of the state of Sikkim-an NE Indian state, with respect to associated demographic factors was investigated. A total of 550 fecal E. coli isolates were collected during July 2015 to June 2017. A structured questionnaire was used to collect data to ascertain the potential factors associated with the carriage of antibiotic resistance E. coli among the children. Statistical analysis along with a logistic regression identified potential external factors affecting the observed antibiotic resistance pattern. The data indicated a high prevalence of resistance to common antibiotics like ampicillin (92%), ceftazidime (90%), cefoxitin (88%), streptomycin (40%) and tetracycline (36%), but no resistance to chloramphenicol. The resistance to the combination of penicillin and quinolone group of antibiotics was observed in fifty-two percent of the isolates. A positive correlation between the harboring of antibiotics resistant E. coli with different demographic factors was observed such as, with children living in nuclear family (vs joint family 63.15%, OR 0.18, 95% CI:0.11-0.28, p < 0.01), below higher secondary maternal education (vs college graduates 59.27% OR 0.75, 95% CI:0.55-1.02, p < 0.02). A close association between different demographic factors and the high prevalence of antibiotic-resistant commensal E. coli in the current study suggests a concern over rising misuse of antibiotics that warrants a future threat of emergence of multidrug-resistant pathogen isolates.
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