ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2018
Intracochlear Pressures in Simulated Otitis Media With Effusion: A Temporal Bone Study.
Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Middle Ear Transfer Function for Sound Conduction Study of Middle Ear Implants: A New Method.Journal of otology · 2025Article
- Methods and reference data for middle ear transfer functions.Scientific reports · 2022Article
- Risks of Intracochlear Pressures From Laser Stapedotomy.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2020Article
- Characterizing Insertion Pressure Profiles During Cochlear Implantation: Simultaneous Fluoroscopy and Intracochlear Pressure Measurements.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2020Article
- A Comparison of Intracochlear Pressures During Ipsilateral and Contralateral Stimulation With a Bone Conduction Implant.Ear and hearingArticle
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
hypothesisSimulated otitis media with effusion reduces intracochlear pressures comparable to umbo velocity.
backgroundOtitis media with effusion is a common cause of temporary hearing loss, particularly in children, producing deficits of 30 to 40 dB. Previous studies measured the effects of simulated effusion on ossicular mechanics; however, no studies have measured cochlear stimulation directly. Here, we compare pressures in the scala vestibuli and tympani to umbo velocity, before and after induction of simulated effusion in cadaveric human specimens.
methodsEight cadaveric, hemi-cephalic human heads were prepared with complete mastoidectomies. Intracochlear pressures were measured with fiber optic pressure probes, and umbo velocity measured via laser Doppler vibrometry (LDV). Stimuli were pure tones (0.1-14 kHz) presented in the ear canal via a custom speculum sealed with a glass cover slip. Effusion was simulated by filling the mastoid cavity and middle ear space with water.
resultsAcoustic stimulation with middle ear effusion resulted in decreased umbo velocity up to ∼26 dB, whereas differential pressure (PDiff) at the base of the cochlea decreased by only ∼16 dB.
conclusionSimulating effusion leads to a frequency-dependent reduction in intracochlear sound pressure levels consistent with audiological presentation and prior reports. Results reveal that intracochlear pressure measurements (PSV and PST) decrease less than expected, and less than the decrease in PDiff. The observed decrease in umbo velocity is greater than in the differential intracochlear pressures, suggesting that umbo velocity overestimates the induced conductive hearing loss. These results suggest that an alternate sound conduction pathway transmits sound to the inner ear during effusion.
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