ArticleEmerging infectious diseases2018
Typhus Group Rickettsiosis, Germany, 2010-2017
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- The diagnostic accuracy of point-of-care nucleic acid-based isothermal amplification assays for scrub typhus: a systematic review and meta-analysis.Frontiers in microbiology · 2024Pooled it
- Rickettsiales in the WHO European Region: an update from a One Health perspective.Parasites & vectors · 2023Pooled it
- Selection of Diagnostic Cutoffs for Murine Typhus IgM and IgG Immunofluorescence Assay: A Systematic Review.The American journal of tropical medicine and hygiene · 2020Pooled it
- Rickettsiosis: existing advances and future opportunities for the development of vaccines.Veterinary research communications · 2026Review
- Rickettsia typhi, Bartonella henselae, and related zoonotic agents in fleas from domestic cats (Felis catus) from the Rio Grande Valley, Texas.Parasites & vectors · 2026Article
- The Paucity of Typical Pathology: An Autopsy Series of Typhus Group Rickettsiosis-Associated Hemophagocytic Lymphohistiocytosis.Pathogens (Basel, Switzerland) · 2026Article
- Seasonal and spatial trends of rickettsioses in Sri Lanka (2009-2023): Spatio-temporal analysis and climate-linked modeling.PloS one · 2026Article
- Rickettsia spp. in finnish ixodid ticks.Parasites & vectors · 2025Article
- Surveillance of Flea-Borne Typhus in California, 2011-2019.The American journal of tropical medicine and hygiene · 2024Article
- Seroprevalence of arthropod-borne bacterial infections in homeless individuals in Hamburg in 2020.Infection · 2023Article
- A case of occupational transmission of mpox.Infection · 2023Article
- Inflammatory cytokine profile and T cell responses in African tick bite fever patients.Medical microbiology and immunology · 2022Article
- Risk factors analysis for neglected human rickettsioses in rural communities in Nan province, Thailand: A community-based observational study along a landscape gradient.PLoS neglected tropical diseases · 2022Observational
- Rickettsiosis in Southeast Asia: Summary for International Travellers during the COVID-19 Pandemic.Tropical medicine and infectious disease · 2022Review
- Molecular Evidence for Flea-Borne Rickettsiosis in Febrile Patients from Madagascar.Pathogens (Basel, Switzerland) · 2021Article
- Sunbathing, a possible risk factor of murine typhus infection in Greece.PLoS neglected tropical diseases · 2021Article
- Article
- Manifestations and Management of Flea-Borne Rickettsioses.Research and reports in tropical medicine · 2021Review
- Case Report: Renal Failure due to Focal Segmental Glomerulosclerosis in a Patient with Murine Typhus.The American journal of tropical medicine and hygiene · 2020Article
- Climate factors driven typhus group rickettsiosis incidence dynamics in Xishuangbanna Dai autonomous prefecture of Yunnan province in China, 2005-2017.Environmental health : a global access science source · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Typhus group rickettsiosis is caused by the vectorborne bacteria Rickettsia typhi and R. prowazekii. R. typhi, which causes murine typhus, the less severe endemic form of typhus, is transmitted by fleas; R. prowazekii, which causes the severe epidemic form of typhus, is transmitted by body lice. To examine the immunology of human infection with typhus group rickettsiae, we retrospectively reviewed clinical signs and symptoms, laboratory changes, and travel destinations of 28 patients who had typhus group rickettsiosis diagnosed by the German Reference Center for Tropical Pathogens, Hamburg, Germany, during 2010-2017. Immunofluorescence assays of follow-up serum samples indicated simultaneous seroconversion of IgM, IgA, and IgG or concurrence in the first serum sample. Cytokine levels peaked during the second week of infection, coinciding with organ dysfunction and seroconversion. For 3 patients, R. typhi was detected by species-specific nested quantitative PCR. For all 28 patients, R. typhi was the most likely causative pathogen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.