Evidence map›Paper›PMID 29912289›Full record

ArticleBiostatistics (Oxford, England)2019

Semi-supervised neighborhoods and localized patient outcome prediction.

Alison E Kosel, Patrick J Heagerty

Abstract read
In one paragraph

Article in Biostatistics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alison E KoselDepartment of Biostatistics, University of Washington, F-600, Health Sciences Building NE Pacific Street, Seattle, WA, USA.
Patrick J HeagertyDepartment of Biostatistics, University of Washington, F-600, Health Sciences Building NE Pacific Street, Seattle, WA, USA.

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Statistical Methods for Longitudinal StudiesR01HL072966 · NHLBI · UNIVERSITY OF WASHINGTON · PI HEAGERTY, PATRICK J · 2003 to 2014
$1.9M
NCATS NIH HHS UL1 TR002319NHLBI NIH HHS R01 HL072966
6 · The paper itself

Abstract

Robust statistical methods that can provide patients and their healthcare providers with individual predictions are needed to help guide informed medical decisions. Ideally an individual prediction would display the full range of possible outcomes (full predictive distribution), would be obtained with a user-specified level of precision, and would be minimally reliant on statistical model assumptions. We propose a novel method that satisfies each of these criteria via the semi-supervised creation of an axis-parallel covariate neighborhood constructed around a given point defining the patient of interest. We then provide non-parametric estimates of the outcome distribution for the subset of subjects in this neighborhood, which we refer to as a localized prediction. We implement local prediction methods using dynamic graphical methods which allow the user to vary key options such as the choice of the variables defining the neighborhood, and the size of the neighborhood.

Indexed as

Models, StatisticalPrognosisBiostatisticsHumansOutcome Assessment, Health CareLocal predictionNon-parametricSemi-supervised learning

Identifiers

PMID29912289
PMCPMC6821385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.