ArticleJournal of visualized experiments : JoVE2018
Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications.
Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Growing Relevance of Decellularized Plant Material as Functional Scaffolds in Tissue Engineering and Cultured Meat: A Scoping Review on Recent Advances, Challenges, and Future Directions.Annals of biomedical engineering · 2026Review
- Decellularized extracellular matrix scaffolds fromMaterials today. Bio · 2025Article
- Engineering vascular grafts from decellularized plants: Advances and challenges.Histology and histopathology · 2025Review
- Plant-Based Scaffolds for Tissue Engineering: A Review.Polymers · 2025Review
- Mechanical Properties and Microstructure of Decellularized Brown Seaweed Scaffold for Tissue Engineering.Bioengineering (Basel, Switzerland) · 2025Article
- Decellularized apple hypanthium as a plant-based biomaterial for cartilage regeneration in vitro: a comparative study of progenitor cell types and environmental conditions.Journal of biological engineering · 2025Article
- Optimization and Standardization of Plant-Derived Vascular Scaffolds.International journal of molecular sciences · 2025Article
- Biocompatibility of decellularized spinach leaves.npj biomedical innovations · 2025Article
- Decellularized Persian walnut leaf (Frontiers in bioengineering and biotechnology · 2025Article
- Decellularized Green and Brown Macroalgae as Cellulose Matrices for Tissue Engineering.Journal of functional biomaterials · 2024Article
- From Nature to Technology: Exploring the Potential of Plant-Based Materials and Modified Plants in Biomimetics, Bionics, and Green Innovations.Biomimetics (Basel, Switzerland) · 2024Review
- Unconventional strategies for liver tissue engineering: plant, paper, silk and nanomaterial-based scaffolds.Regenerative medicine · 2024Review
- Plant Decellularization by Chemical and Physical Methods for Regenerative Medicine: A Review Article.Journal of medical signals and sensors · 2024Review
- Decellularized Scaffolds of Nopal (Journal of functional biomaterials · 2023Article
- Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review.Bioengineering (Basel, Switzerland) · 2022Review
- Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation.Cellular and molecular bioengineering · 2022Article
- Application of 3D Bioprinting in Urology.Micromachines · 2022Review
- Scaffolding Biomaterials for 3D Cultivated Meat: Prospects and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Decellularized fennel and dill leaves as possible 3D channel network in GelMA for the development of anFrontiers in bioengineering and biotechnology · 2022Article
- The Emerging Role of Decellularized Plant-Based Scaffolds as a New Biomaterial.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The autologous, synthetic, and animal-derived grafts currently used as scaffolds for tissue replacement have limitations due to low availability, poor biocompatibility, and cost. Plant tissues have favorable characteristics that make them uniquely suited for use as scaffolds, such as high surface area, excellent water transport and retention, interconnected porosity, preexisting vascular networks, and a wide range of mechanical properties. Two successful methods of plant decellularization for tissue engineering applications are described here. The first method is based on detergent baths to remove cellular matter, which is similar to previously established methods used to clear mammalian tissues. The second is a detergent-free method adapted from a protocol that isolates leaf vasculature and involves the use of a heated bleach and salt bath to clear the leaves and stems. Both methods yield scaffolds with comparable mechanical properties and low cellular metabolic impact, thus allowing the user to select the protocol which better suits their intended application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.