ArticleMolecules (Basel, Switzerland)2018
Vasodilator Activity of Compounds Isolated from Plants Used in Mexican Traditional Medicine.
Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
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- Corosolic acid alleviates rheumatoid arthritis by down regulation of the NF-κB/PI3K/AKT signaling pathway.Scientific reports · 2026Article
- A review of the pharmacological mechanism of corosolic acid.Frontiers in pharmacology · 2026Review
- Phytochemical Profile, Vasodilatory and Biphasic Effects on Intestinal Motility, and Toxicological Evaluation of the Methanol and Dichloromethane Extracts from the Aerial Parts ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Antibacterial Activity and Molecular Docking of Lignans Isolated fromPharmaceuticals (Basel, Switzerland) · 2025Article
- Molecular Modeling of Vasodilatory Activity: Unveiling Novel Candidates Through Density Functional Theory, QSAR, and Molecular Dynamics.International journal of molecular sciences · 2024Article
- Vasorelaxant effects of biochemical constituents of various medicinal plants and their benefits in diabetes.World journal of diabetes · 2024Review
- 3'-Demethoxy-6-O-Demethylisoguaiacin and Norisoguaiacin Nematocidal Lignans fromPlants (Basel, Switzerland) · 2023Article
- Chromatographic Techniques and Pharmacological Analysis as a Quality Control Strategy forPharmaceuticals (Basel, Switzerland) · 2022Article
- State-of-the-Art and Opportunities for Bioactive Pentacyclic Triterpenes from Native Mexican Plants.Plants (Basel, Switzerland) · 2022Review
- Study on the Chemical Composition and the Biological Activities ofMolecules (Basel, Switzerland) · 2022Article
- Development of a quantified herbal extract of hawthornSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Phytochemical analysis and versatile in vitro evaluation of antimicrobial, cytotoxic and enzyme inhibition potential of different extracts of traditionally used Aquilegia pubiflora Wall. Ex Royle.BMC complementary medicine and therapies · 2021Article
- Article
- Vasorelaxant Effect ofPlants (Basel, Switzerland) · 2020Article
- Marjoram Relaxes Rat Thoracic Aorta Via a PI3-K/eNOS/cGMP Pathway.Biomolecules · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial hypertension is one of the main risk factors in the development of cardiovascular diseases. Therefore, it is important to look for new drugs to treat hypertension. In this study, we carried out the screening of 19 compounds (triterpenes, diterpenes, sesquiterpenes, lignans, and flavonoids) isolated from 10 plants used in Mexican traditional medicine to determine whether they elicited vascular smooth muscle relaxation and, therefore, could represent novel anti-hypertension drug candidates. The vasorelaxant activity of these compounds was evaluated on the isolated rat aorta assay and the results obtained from this evaluation showed that three compounds induced a significant vasodilatory effect:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.