Evidence map›Paper›PMID 29911516›Full record

SynthesisPublic health nutrition2018

Sex consideration in diet-biomarker-related indices: a systematic review.

Sihan Song, Sejin Kim, Jung Eun Lee

Abstract readSystematic Review
In one paragraph

Synthesis in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sihan Song1Department of Food and Nutrition, College of Human Ecology,Seoul National University,1 Gwanak-ro, Gwanak-gu, Seoul 08826,Republic of Korea.
Sejin Kim1Department of Food and Nutrition, College of Human Ecology,Seoul National University,1 Gwanak-ro, Gwanak-gu, Seoul 08826,Republic of Korea.
Jung Eun Lee1Department of Food and Nutrition, College of Human Ecology,Seoul National University,1 Gwanak-ro, Gwanak-gu, Seoul 08826,Republic of Korea.ORCID 0000-0003-1141-878X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAn index of biomarkers derived from dietary factors (diet-biomarker-related index) identifies foods and nutrients that encompass physiological potentials and provides scientific evidence for dietary patterns that increase the risk of disease associated with specific biomarkers. Although men and women have different dietary patterns and physiological characteristics, sex is not often considered when investigators develop a diet-biomarker-related index. We aimed to review whether epidemiological studies developed diet-biomarker-related indices in a sex-specific way.

designWe systematically searched for epidemiological studies that developed diet-biomarker-related indices, including (i) biomarker prediction indices that include dietary factors as explanatory variables and (ii) dietary patterns to explain biomarker variations, in the PubMed and EMBASE databases. We qualitatively reviewed the sex consideration in index development.

resultsWe identified seventy-nine studies that developed a diet-biomarker-related index. We found that fifty-four studies included both men and women. Of these fifty-four studies, twenty-nine (53·7 %) did not consider sex, eleven (20·3 %) included sex in the development model, seven (13·0 %) considered sex but did not include sex in the development model, and seven (13·0 %) derived a diet-biomarker-related index for men and women separately. A list of selected dietary factors that explained levels of biomarkers generally differed by sex in the studies that developed a diet-biomarker-related index in a sex-specific way.

conclusionsMost studies that included both men and women did not develop the diet-biomarker-related index in a sex-specific way. Further research is needed to identify whether a sex-specific diet-biomarker-related index is more predictive of the disease of interest than an index without sex consideration.

Indexed as

DietNutritional Physiological PhenomenaBiomarkersFemaleHumansMaleSex FactorsBiomarkersBiomarkerDietDiet–biomarker-related indexNutritional epidemiologySex

Identifiers

PMID29911516
PMCPMC10260765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.