Evidence map›Paper›PMID 29911296›Full record

ReviewBiomechanics and modeling in mechanobiology2018

Structural modelling of the cardiovascular system.

Benjamin Owen, Nicholas Bojdo, Andrey Jivkov, Bernard Keavney, Alistair Revell

Abstract readReview
In one paragraph

Review in Biomechanics and modeling in mechanobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. A simulation environment for robot-assisted endovascular interventions.International journal of computer assisted radiology and surgery · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin OwenSchool of Mechanical, Aerospace and Civil Engineering, University of Manchester, George Begg Building, Manchester, M1 3BB, UK. benjamin.owen@manchester.ac.uk.ORCID http://orcid.org/0000-0003-1948-9160
Nicholas BojdoSchool of Mechanical, Aerospace and Civil Engineering, University of Manchester, George Begg Building, Manchester, M1 3BB, UK.ORCID http://orcid.org/0000-0001-8861-4231
Andrey JivkovSchool of Mechanical, Aerospace and Civil Engineering, University of Manchester, George Begg Building, Manchester, M1 3BB, UK.ORCID http://orcid.org/0000-0002-3454-7341
Bernard KeavneyDivision of Cardiovascular Sciences, University of Manchester, AV Hill Building, Manchester, M13 9PT, UK.ORCID http://orcid.org/0000-0001-9573-0812
Alistair RevellSchool of Mechanical, Aerospace and Civil Engineering, University of Manchester, George Begg Building, Manchester, M1 3BB, UK.ORCID http://orcid.org/0000-0001-7435-1506

Funding

British Heart Foundation RG/15/12/31616Medical Research Council DGEMBEMedical Research Council MR/P025463/1
6 · The paper itself

Abstract

Computational modelling of the cardiovascular system offers much promise, but represents a truly interdisciplinary challenge, requiring knowledge of physiology, mechanics of materials, fluid dynamics and biochemistry. This paper aims to provide a summary of the recent advances in cardiovascular structural modelling, including the numerical methods, main constitutive models and modelling procedures developed to represent cardiovascular structures and pathologies across a broad range of length and timescales; serving as an accessible point of reference to newcomers to the field. The class of so-called hyperelastic materials provides the theoretical foundation for the modelling of how these materials deform under load, and so an overview of these models is provided; comparing classical to application-specific phenomenological models. The physiology is split into components and pathologies of the cardiovascular system and linked back to constitutive modelling developments, identifying current state of the art in modelling procedures from both clinical and engineering sources. Models which have originally been derived for one application and scale are shown to be used for an increasing range and for similar applications. The trend for such approaches is discussed in the context of increasing availability of high performance computing resources, where in some cases computer hardware can impact the choice of modelling approach used.

Indexed as

Cardiovascular SystemModels, CardiovascularAneurysm, RupturedAnimalsAnisotropyAtherosclerosisBiocompatible MaterialsComputer SimulationCoronary VesselsElasticityErythrocytesHeartHeart DiseasesHeart ValvesHumansHydrodynamicsBiocompatible MaterialsCardiovascular structureContinuumDiscreteModelling

Identifiers

PMID29911296
PMCPMC6154127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.