Evidence map›Paper›PMID 29911074›Full record

Trial reportFrontiers in cellular and infection microbiology2018

Macrophage Activation Marker Neopterin: A Candidate Biomarker for Treatment Response and Relapse in Visceral Leishmaniasis.

Anke E Kip, Monique Wasunna, Fabiana Alves, Jan H M Schellens, Jos H Beijnen, Ahmed M Musa, Eltahir A G Khalil, Thomas P C Dorlo

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Molecular Tracking of theFrontiers in cellular and infection microbiology · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Anke E KipDepartment of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/the Netherlands Cancer Institute, Amsterdam, Netherlands.
Monique WasunnaDrug for Neglected Diseases Initiative, Nairobi, Kenya.
Fabiana AlvesDrug for Neglected Diseases Initiative, Geneva, Switzerland.
Jan H M SchellensDivision of Pharmacoepidemiology & Clinical Pharmacology, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.
Jos H BeijnenDepartment of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/the Netherlands Cancer Institute, Amsterdam, Netherlands.
Ahmed M MusaInstitute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Eltahir A G KhalilInstitute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Thomas P C DorloDepartment of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/the Netherlands Cancer Institute, Amsterdam, Netherlands.
The Netherlands Cancer Institute · NLUniversity of Khartoum · SDDrugs for Neglected Diseases Initiative · CHKenya AIDS Vaccine Initiative · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

BiomarkersMacrophage ActivationAdolescentAdultAmphotericin BChildDrug CombinationsFemaleHumansKenyaKineticsLeishmaniasis, VisceralMaleMiddle AgedMulticenter Studies as TopicNeopterinAmphotericin BBiomarkersDrug Combinationsliposomal amphotericin BmiltefosineNeopterinPhosphorylcholinebiomarkerkala-azarliposomal amphotericin Bmacrophage activationmiltefosineneopterinpharmacodynamicsvisceral leishmaniasis

Identifiers

PMID29911074
PMCPMC5992270
OpenAlexW2807637367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.