Evidence map›Paper›PMID 29911004›Full record

ArticleJournal of cardiovascular echography

Measurement of Mouse Heart Rate Variability using Echocardiographic System.

Filipe Fernandes Stoyell-Conti, Fernando Santos, Jacqueline Freire Machi, Diana Rosa Hernandez, Catarina Andrade Barboza, Maria-Cláudia Irigoyen, Kátia De Angelis, Mariana Morris

Abstract read
In one paragraph

Article in Journal of cardiovascular echography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Cardiovascular function and autonomic regulation in urethane-anesthetized and conscious mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. A method to assess heart rate variability in neonate rats: validation in normotensive and hypertensive animals.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Filipe Fernandes Stoyell-ContiLaboratory of Translational Physiology, Nove de Julho University, Sao Paulo, Brazil.
Fernando SantosInstitute of Neuro-Immune Medicine, Nova Southeastern University, FL, USA.
Jacqueline Freire MachiInstitute of Neuro-Immune Medicine, Nova Southeastern University, FL, USA.
Diana Rosa HernandezInstitute of Neuro-Immune Medicine, Nova Southeastern University, FL, USA.
Catarina Andrade BarbozaInstitute of Neuro-Immune Medicine, Nova Southeastern University, FL, USA.
Maria-Cláudia IrigoyenHypertension Unit, Heart Institute (InCor), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Kátia De AngelisLaboratory of Translational Physiology, Nove de Julho University, Sao Paulo, Brazil.
Mariana MorrisInstitute of Neuro-Immune Medicine, Nova Southeastern University, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe employed an echocardiographic (ECHO) system as the backbone for the collection of electrocardiogram (ECG) and heart rate variability (HRV) data. The system was tested using an exercise model in which C57 male mice were exposed to sham or forced wheel running.

methodsPeak/peak (RR) interval was recorded over a 3 min period using the ECG platform of the ECHO system. Isoflurane-anesthetized male mice were divided into two groups (

conclusionResults document the utility of combining the ECHO and the ECG platform, allowing for the dual measurement of autonomic and cardiac function in mice.

Indexed as

Echocardiographyelectrocardiogramexercises trainingheart rate variabilitymicenoninvasive method

Identifiers

PMID29911004
PMCPMC5989555

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.