Evidence map›Paper›PMID 29910836›Full record

ArticleEcancermedicalscience2018

Neoplasm of uncertain behaviour of the breast-a retrospective study in a breast unit.

Xavier de Sousa, Pedro Santos Ferreira, Luís Branco, Jorge Simões, Matilde Gonçalves, Manuel Vítor Rigueira, Luís Cortez

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Pricing of innovative medicines and advanced therapies worldwide: an scoping review.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xavier de SousaGeneral Surgery Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Pedro Santos FerreiraBreast Unit, General Surgery Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Luís BrancoBreast Unit, General Surgery Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Jorge SimõesBreast Unit, Obstetrics and Gynaecology Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Matilde GonçalvesPathology Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Manuel Vítor RigueiraBreast Unit, General Surgery Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Luís CortezGeneral Surgery Department, Setúbal Hospital Centre, São Bernardo Hospital, 2910-446 Setúbal, Portugal.
Hospital de São Bernardo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBreast lesions include a heterogeneous group of entities with variable clinical behaviour and morphological presentation, mostly classified as benign or malignant, with predictable behaviour. However, there are lesions with clinical, breast imaging and/or biopsy characteristics that do not clarify their nature. These lesions have an uncertain behaviour regarding their malignant potential at diagnosis.We intend to relate the preoperative diagnosis of neoplasm of uncertain behaviour of the breast (NUnBB) regarding the core needle biopsy and the histological result after excisional biopsy.

methodsThis is a retrospective study of patients submitted to local excision of breast lesions with a perioperative diagnosis of NUnBB, classified as 2383 at 'International Statistical Classification of Diseases and Related Health Problems' (ICD 9), between January 2007 and October 2016 in a breast unit.

resultsNinety-two cases with the diagnosis of NUnBB were analysed: 91 females with a mean age of 59 ± 14 years. All were submitted to local excision of breast lesion as ambulatory surgery with the following histology: 64% benign, 3% malignant potential and 33% malignant. Of those who presented malignant results, 69% underwent a surgical re-intervention for local control of the disease. DISCUSSION: Regarding the considerable number of malignant lesions at final histology and the high percentage of which are re-operated, NUnBB should be treated with the same priority as a confirmed malignant neoplasm and whenever possible, using the most appropriate surgical technique.

Indexed as

core needle biopsyexcisional biopsymalignant potentialneoplasm of uncertain behaviour of the breast

Identifiers

PMID29910836
PMCPMC5985751
OpenAlexW2805276254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.