Evidence map›Paper›PMID 29910812›Full record

ReviewFrontiers in immunology2018

Effector T Helper Cell Subsets in Inflammatory Bowel Diseases.

Tanbeena Imam, Sungtae Park, Mark H Kaplan, Matthew R Olson

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Effect ofTherapeutic advances in gastroenterology · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanbeena ImamDepartment of Pediatrics and Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, United States.
Sungtae ParkDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Mark H KaplanDepartment of Pediatrics and Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, United States.
Matthew R OlsonDepartment of Pediatrics and Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, United States.

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
The role of PU.1 in T helper cell heterogeneityR01AI057459 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI KAPLAN, MARK H · 2005 to 2025
$8.2M
Cytokine regulation of skin barrier functionR01AI095282 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI KAPLAN, MARK H · 2012 to 2022
$4.3M
Indiana Clinical and Translational Sciences InstituteTL1TR001107 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$2.0M
Th9 cells in immediate hypersensitivityR01AI129241 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI KAPLAN, MARK H · 2017 to 2021
$2.0M
Granzyme A-secreting T cells in allergic inflammationR21AI117380 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI KAPLAN, MARK H · 2015 to 2016
$429k
NCATS NIH HHS TL1 TR001107NCATS NIH HHS UL1 TR001108NIAID NIH HHS R01 AI057459NIAID NIH HHS R01 AI095282NIAID NIH HHS R01 AI129241NIAID NIH HHS R21 AI117380
6 · The paper itself

Abstract

The gastrointestinal tract is a site of high immune challenge, as it must maintain a delicate balance between tolerating luminal contents and generating an immune response toward pathogens. CD4

Indexed as

AnimalsBiomarkersCytokinesDisease SusceptibilityGene Expression RegulationHumansImmunotherapyInflammatory Bowel DiseasesLymphocyte CountMolecular Targeted TherapySignal TransductionT-Lymphocytes, Helper-InducerT-Lymphocyte SubsetsBiomarkersCytokinesCrohn’s diseaseinflammatory bowel diseaseinflammatory cytokinesT helper cellstranscription factorsulcerative colitis

Identifiers

PMID29910812
PMCPMC5992276

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.