Evidence map›Paper›PMID 29910691›Full record

ArticleThe Cochrane database of systematic reviews2018

Symptom screening for active tuberculosis in pregnant women living with HIV.

Sylvia M LaCourse, Lisa M Cranmer, Adrie Bekker, Karen R Steingart, Danae Black, David J Horne, Eyal Oren, Sherri Pals, Surbhi Modi, Jyoti Mathad

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Cochrane database of systematic reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Subclinical tuberculosis and adverse infant outcomes in pregnant women with HIV.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2020
    Article
  4. Detecting tuberculosis in pregnant and postpartum women in Eswatini.African journal of laboratory medicine · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sylvia M LaCourseDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.
Lisa M CranmerDepartment of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Adrie BekkerDepartment of Paediatrics, Stellenbosch University, Cape Town, South Africa.
Karen R SteingartCochrane Infectious Diseases Group, Liverpool School of Tropical Medicine, Liverpool, UK.
Danae BlackDepartment of Epidemiology, University of Washington, Seattle, Washington, USA.
David J HorneDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, and Firland Northwest TB Center, University of Washington, Seattle, WA, USA.
Eyal OrenDivision of Epidemiology and Biostatistics, San Diego State University, San Diego, California, USA.
Sherri PalsDivision of Global HIV and Tuberculosis, Center for Global Health, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Surbhi ModiDivision of Global HIV and Tuberculosis, Center for Global Health, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Jyoti MathadDepartment of Medicine, Division of Infectious Diseases, Center for Global Health, Weill Cornell Medical College, New York, USA.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Florian Hladik · 1988 to 2026
$104.9M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Impact of Immune Changes of Pregnancy on TuberculosisR01HD081929 · NICHD · JOHNS HOPKINS UNIVERSITY · PI GUPTA, AMITA · 2014 to 2017
$1.7M
Effect of pregnancy and HIV on the development of tuberculosisK23AI129854 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI MATHAD, JYOTI S · 2017 to 2021
$1.0M
Impact of maternal HIV on Mycobacterium tuberculosis infection among peripartum women and their infantsK23AI120793 · NIAID · UNIVERSITY OF WASHINGTON · PI LACOURSE, SYLVIA · 2016 to 2020
$910k
Tuberculosis Infection and Genetic VariationK23AI085036 · NIAID · UNIVERSITY OF WASHINGTON · PI HORNE, DAVID J. · 2010 to 2014
$638k
NIAID NIH HHS K23 AI085036NIAID NIH HHS K23 AI120793NIAID NIH HHS K23 AI129854NIAID NIH HHS P30 AI027757NIAID NIH HHS T32 AI007140NICHD NIH HHS R01 HD081929
6 · The paper itself

Abstract

Editorial note This protocol will not progress to review stage as it no longer meets Cochrane's methodological standards. This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To assess the accuracy of the four-symptom screen (cough, fever, night sweats, or weight loss) for identifying active TB in pregnant PLHIV who are screened in an outpatient or community setting. To investigate potential sources of heterogeneity of the accuracy of the four-symptom screen between studies including: ART status, CD4 cell count, gestational age, pregnancy stage (pregnancy vs. postpartum), screening test definition of cough (any cough vs. cough greater than 2 weeks).To describe the accuracy of single symptoms included within the four-symptom screen, additioal symptoms or symptom combinations, for identifying active TB in pregnant PLHIV. For example, additional symptoms may include failure to gain weight or fatigue.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousSystematic Reviews as TopicTuberculosisFemaleHumansPregnancy

Identifiers

PMID29910691
PMCPMC5997280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.