ReviewInternational journal of biological sciences2018
Health risks associated with genetic alterations in internal clock system by external factors.
Review in International journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 49 citations in OpenAlex.
- Influence of Time of Day on Skin Microvascular Response to Post-Occlusive Reactive Hyperemia.Journal of clinical medicine · 2026Article
- Intensive care unit nurses' perceptions of night-work-related chronic fatigue and cognitive function: a cross-sectional survey.Frontiers in public health · 2026Article
- Multilevel analysis of sleep arrangements and psychological well-being among older couples in Taiwan.BMC public health · 2025Article
- Relationship Between Sleep Duration and Psychosocial Well-Being in Healthcare Personnel: Identification of Predictors and Vulnerability Patterns.Behavioral sciences (Basel, Switzerland) · 2025Article
- Integrating Assessment of Circadian Rhythmicity to Improve Treatment Outcomes for Circadian Rhythm Sleep-Wake Disorders: Updates on New Treatments.Current sleep medicine reports · 2025Review
- Gene expression clock: an unsupervised deep learning approach for predicting circadian rhythmicity from whole genome expression.Neural computing & applications · 2024Article
- Circadian Regulation of Lipid Metabolism during Pregnancy.International journal of molecular sciences · 2024Review
- Review
- Review
- PENN: Phase Estimation Neural Network on Gene Expression Data.The 4th Joint International Conference on Deep Learning, Big Data and Blockchain (DBB 2023). Joint International Conference on Deep Learning, Big Data and Blockchain (4th : 2023 : Marrakech, Morocco ; Online) · 2023Article
- Circadian rhythm as a key player in cancer progression as well as a therapeutic target inFrontiers in oncology · 2023Review
- The role of circadian clock-controlled mitochondrial dynamics in diabetic cardiomyopathy.Frontiers in immunology · 2023Review
- Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution.Antioxidants & redox signaling · 2022Review
- Exploring polygenic-environment and residual-environment interactions for depressive symptoms within the UK Biobank.Genetic epidemiology · 2022Article
- Alignment between glioblastoma internal clock and environmental cues ameliorates survival in Drosophila.Communications biology · 2022Article
- Night shift work characteristics are associated with several elevated metabolic risk factors and immune cell counts in a cross-sectional study.Scientific reports · 2022Article
- Bright Light Therapy for Parkinson Disease: A Literature Review and Meta-Analysis of Randomized Controlled Trials.Biology · 2021Article
- Study of Post-COVID-19 Syndrome in Saudi Arabia.Cureus · 2021Article
- Mental health consequences of infections by coronaviruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Brain and behavior · 2021Review
- Influence of mental stress and environmental toxins on circadian clocks: Implications for redox regulation of the heart and cardioprotection.British journal of pharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian system maintains the main aspects of physiological and behavioral processes. Both circadian rhythm and sleep impact an organism's health through interaction with environmental factors. Variations in external factors influence the functionality of clock genes and disrupt 24-hour rhythmic cycle. The disrupted circadian rhythm and disregulated sleep affect an organism's health, thereby causing several disorders including cancer, depression and cardiac disorders. Considering the role of clock genes and environmental factors, extensive investigation is required focusing on pathways involved in development of life-threatening disorders. This review identifies the major risks and associated factors related with disruption in circadian system and sleep.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.