ArticleInfection and drug resistance2018
Epidemiology, practice patterns, and prognostic factors for candidemia; and characteristics of fourteen patients with breakthrough
Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Clinical and molecular features of candidemia: a three-year retrospective study in Northern Guizhou, China.Frontiers in cellular and infection microbiology · 2025Article
- 30-day mortality in invasive candidiasis and candidemia in a multidisciplinary hospital in Moscow, Russia.Current medical mycology · 2025Article
- Breakthrough candidemia with hematological disease: Results from a single-center retrospective study in Japan, 2009-2020.Medical mycology · 2023Article
- Non-Journal of fungi (Basel, Switzerland) · 2022Review
- Isolation of antifungal-resistant yeasts from bulk milk in Japan.The Journal of veterinary medical science · 2021Article
- Emerging Prospects for Combating Fungal Infections by Targeting Phosphatidylinositol Transfer Proteins.International journal of molecular sciences · 2021Review
- A predictive nomogram for mortality of cancer patients with invasive candidiasis: a 10-year study in a cancer center of North China.BMC infectious diseases · 2021Observational
- Case Report: AFrontiers in medicine · 2021Article
- Genetic Basis of Azole and Echinocandin Resistance in Clinical Candida glabrata in Japan.Antimicrobial agents and chemotherapy · 2020Article
- Candidemia due toCurrent medical mycology · 2019Article
- Epidemiology and prognostic factors of nosocomial candidemia in Northeast Brazil: A six-year retrospective study.PloS one · 2019Article
- Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment.Infection and drug resistance · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandidemia is associated with high mortality, and its prognostic factors need to be examined in more detail in order to improve its management. A case of breakthrough (BT) candidemia is defined as the development of candidemia during antifungal therapy. The microbiological characteristics of and appropriate clinical practices for BT candidemia remain unclear.
objectivesThe primary objective of the present study was to identify the prognostic factors of candidemia, while the secondary objective was to elucidate the microbiological characteristics of patients with BT candidemia. MATERIALS AND
methodsA total of 121 patients diagnosed with candidemia between January 2007 and December 2016 were enrolled in this study. The primary outcome was the 30-day mortality rate.
resultsThe overall incidence of candidemia was 0.056 cases/1000 inpatients. Among the 126
conclusionThe prompt initiation of antifungal therapy and removal of central venous catheter were essential for better outcomes. A class switch to other antifungal agents needs to be considered in empirical antifungal therapy for BT candidemia with a history of exposure to azole antifungal agents.
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