Evidence map›Paper›PMID 29910604›Full record

ArticleDrug design, development and therapy2018

AMPK/AS160 mediates tiliroside derivatives-stimulated GLUT4 translocation in muscle cells.

Chang Zhang, Yue Jiang, Jia Liu, Meina Jin, Nan Qin, Ying Chen, Wenyan Niu, Hongquan Duan

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
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  7. Potentilloside A, a New Flavonol-Plants (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Frontiers in pharmacology · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chang ZhangSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Yue JiangSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Jia LiuSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Meina JinSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Nan QinSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Ying ChenSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Wenyan NiuDepartment of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Metabolic Diseases Hospital, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Hongquan DuanSchool of Pharmacy, Research Center of Basic Medical Science, Tianjin Medical University, Tianjin 300070, People's Republic of China.
Tianjin Medical University · CNTianjin Infectious Diseases Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Chinese herb MATERIALS AND

methodsWe explored the effects of tiliroside derivatives on cell surface GLUT4 level (GLUT4 translocation) and the underlying mechanism in L6-GLUT4

resultsWe showed that tiliroside derivatives D1-22 stimulated GLUT4

conclusionTiliroside derivatives D1, D8 and D18 stimulated GLUT4

Indexed as

AMP-Activated Protein KinasesAnimalsCells, CulturedFlavonoidsGlucose Transporter Type 4GTPase-Activating ProteinsInsulin ResistanceMuscle, SkeletalProtein TransportRatsAMP-Activated Protein KinasesFlavonoidsGlucose Transporter Type 4GTPase-Activating ProteinsTBC1D4 protein, humantilirosideAMPKinsulin resistanceskeletal muscle cellstype 2 diabetes

Identifiers

PMID29910604
PMCPMC5989705
OpenAlexW2805559031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.