Evidence map›Paper›PMID 29910549›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2018

Experience with β-D-Glucan Assay in the Management of Critically ill Patients with High Risk of Invasive Candidiasis: An Observational Study.

Nitin Bansal, Ram Gopalakrishnan, Nandini Sethuraman, Nagarajan Ramakrishnan, P Senthur Nambi, D Suresh Kumar, R Madhumitha, M A Thirunarayan, V Ramasubramanian

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Optimizing the Treatment of Critically Ill Patients Utilizing Beta-D-glucan: The Time is Now.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  2. Article
  3. Clinical Profile of Non-neutropenic Patients with Invasive Candidiasis: A Retrospective Study in a Tertiary Care Center.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Nitin BansalInstitiute of Infectious Diseases, Chennai, Tamil Nadu, India.
Ram GopalakrishnanInstitiute of Infectious Diseases, Chennai, Tamil Nadu, India.
Nandini SethuramanDepartment of Microbiology, Apollo Hospitals, Chennai, Tamil Nadu, India.
Nagarajan RamakrishnanInstitute of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
P Senthur NambiInstitiute of Infectious Diseases, Chennai, Tamil Nadu, India.
D Suresh KumarInstitiute of Infectious Diseases, Chennai, Tamil Nadu, India.
R MadhumithaInstitiute of Infectious Diseases, Chennai, Tamil Nadu, India.
M A ThirunarayanDepartment of Microbiology, Apollo Hospitals, Chennai, Tamil Nadu, India.
V RamasubramanianInstitiute of Infectious Diseases, Chennai, Tamil Nadu, India.
Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe (1,3)-β-D-glucan assay (BDG) is recommended for the early diagnosis of invasive candidiasis (IC).

methodsRecords of 154 critically ill adults with suspected IC, on whom BDG was done, were analyzed. Patients were divided into three groups: Group A (confirmed IC), Group B (alternative diagnosis or cause of severe sepsis), and Group C (high candidal score and positive BDG [>80 pg/mL] but without a confirmed diagnosis of IC).

resultsMean BDG levels were significantly higher in Group A (

conclusionA BDG value of <80 pg/ml facilitates early discontinuation of empirical antifungal therapy, with considerable cost savings.

Indexed as

Antifungal stewardshipinvasive candidiasisβ-D-glucan

Identifiers

PMID29910549
PMCPMC5971648
OpenAlexW2804023955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.