Evidence map›Paper›PMID 29910543›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2018

Clinicohematological Profile of Febrile Neutropenia in Childhood Acute Leukemia and Utility of Serum Procalcitonin Levels in Neutropenic Patients.

Rajan Kapoor, Ashish K Simalti, Shuvendu Roy, Pulkit Agarwal

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rajan KapoorDepartment of Hematology, Army Hospital (R and R), New Delhi, India.
Ashish K SimaltiDepartment of Paediatrics, Army Hospital (R and R), New Delhi, India.
Shuvendu RoyDepartment of Paediatrics, Army Hospital (R and R), New Delhi, India.
Pulkit AgarwalDepartment of Paediatrics, Army Hospital (R and R), New Delhi, India.
Army Hospital Research and Referral · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study was planned to explore the clinical and hematological profile of febrile neutropenia (FN) in Indian children with focus on correlation of degree of neutropenia with fever and procalcitonin (PCT) level and the utility of serum PCT levels in cases of FN. MATERIALS AND

methodsChildren below 12 years, receiving chemotherapy for hematological malignancy having oral temperature more than 100°F and absolute neutrophil count (ANC) below 500/mm

resultsFour categories were made based on serum PCT levels which had negative correlation with ANC but no correlation with microbiologically detected infections. DISCUSSION: PCT is generally used to support the diagnosis of bacterial infection or sepsis in the emergency department or to monitor the treatment of sepsis with regard to reviewing antimicrobial treatment. The use of PCT has been well established as a marker for infection in adults and in nonneutropenic children, but similar data are lacking in pediatric population, more so in children with FN in Indian contexts. This study aims to fulfill this lacuna.

conclusionThe higher levels of PCT had a high negative correlation with ANC but low correlation with microbiologically detected infections.

Indexed as

Feverneutropeniaprocalcitonin

Identifiers

PMID29910543
PMCPMC5971642
OpenAlexW2803457848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.