ReviewSports (Basel, Switzerland)2017
Acute and Chronic Effects of Isometric Handgrip Exercise on Cardiovascular Variables in Hypertensive Patients: A Systematic Review.
Review in Sports (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05240144 (Effect of Isometric Handgrip Exercises on Blood Pressure of Hypertensive Adults), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Isometric Handgrip Exercises on Blood Pressure of Hypertensive Adults
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Can postexercise hypotension also be observed in African and Asian populations: a systematic review and meta-analysis of randomized controlled trials.Journal of human hypertension · 2023Pooled it
- Acute Blood Pressure Response to Different Types of Isometric Exercise: A Systematic Review with Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Effect of isometric handgrip exercise on cognitive function: Current evidence, methodology, and safety considerations.Frontiers in physiology · 2022Pooled it
- Effects of Isometric Handgrip Training in Patients With Peripheral Artery Disease: A Randomized Controlled Trial.Journal of the American Heart Association · 2020Trial
- Acute blood pressure responses after different isometric handgrip protocols in hypertensive patients.Clinics (Sao Paulo, Brazil) · 2018Trial
- Effects of isometric handgrip training on blood pressure among hypertensive patients seen within public primary healthcare: a randomized controlled trial.Sao Paulo medical journal = Revista paulista de medicinaTrial
- Efficacy and Cost-Effective Treatment of Isometric Resistance Training for Blood Pressure Control: A Narrative Review in Healthy Individuals and People with Cardiovascular Diseases.Journal of functional morphology and kinesiology · 2026Review
- Rethinking Isometric Handgrip Exercise Prescription: A Commentary on Duration, Fatigue, and Blood Pressure Management.Health science reports · 2026Article
- Effects of the Intensity, Duration, and Muscle Mass of Isometric Handgrip Exercise on Neuromuscular Fatigue and Post-Exercise Blood Pressure Responses: A Crossover Study.Health science reports · 2026Article
- Acute effects of ischemic preconditioning and isometric exercise on blood pressure in prehypertensive males.Journal of exercise science and fitness · 2025Article
- Trends and Scientific Production on Isometric Training: A Bibliometric Analysis.Sports (Basel, Switzerland) · 2025Review
- Rating of perceived exertion versus heart rate for isometric exercise prescription: Reliability and agreement study.Sao Paulo medical journal = Revista paulista de medicina · 2025Article
- Sex-based comparison of the blood pressure, haemodynamic and cardiac autonomic adaptations following isometric exercise training in sedentary adults: a randomised controlled trial.BMJ open sport & exercise medicine · 2025Article
- Acute effects of isometric plank exercise on 24-hour ambulatory blood pressure in young adults with prehypertension: a randomized cross-over trial.Clinical hypertension · 2025Article
- The Western and Chinese exercise training for blood pressure reduction among hypertensive patients: An overview of systematic reviews.Journal of clinical hypertension (Greenwich, Conn.) · 2024Review
- Isometric Exercise Training and Arterial Hypertension: An Updated Review.Sports medicine (Auckland, N.Z.) · 2024Review
- Acute cardiac autonomic and haemodynamic responses to leg and arm isometric exercise.European journal of applied physiology · 2022Article
- Cardiovascular and autonomic dysfunction in long-COVID syndrome and the potential role of non-invasive therapeutic strategies on cardiovascular outcomes.Frontiers in medicine · 2022Article
- Physical Exercise in Resistant Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in cardiovascular medicine · 2022Review
- Tapering and Peaking Maximal Strength for Powerlifting Performance: A Review.Sports (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to describe, through a systematic review, the acute and chronic effects of isometric handgrip exercise on cardiovascular variables in hypertensive individuals. In this systematic review, we included studies that analyzed whether a single bout or a program with isometric exercises affect cardiovascular variables in hypertensive adults. The electronic database PubMed/Medline was searched for relevant studies published until May 2017. Of the 2927 studies initially identified, 2916 were excluded based on title and abstract and five on the basis of full-text assessment, leaving six studies remaining. In addition, one further study cited in the references of the included articles was included in this review, totaling seven studies included (five studies on the chronic effects of isometric handgrip exercise on cardiovascular parameters). None of the acute studies observed post-exercise hypotension. The majority of the chronic studies found decreases in office blood pressure after isometric handgrip training, with training ranging from 6 to 10 weeks, while heart rate variability parameters were improved in one study and did not change in another. Reduction in oxidative stress was observed; however, this variable was only analyzed in one study. In hypertensives, acute responses to isometric handgrip exercise are very limited due to the small number of studies, therefore more research is required. Furthermore, chronic isometric handgrip training reduces blood pressure; however, there is still a gap in the knowledge on the effects of this modality of exercise on other cardiovascular variables-such as endothelial function, oxidative stress, and cardiac autonomic modulation-which should be addressed in future studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.