Evidence map›Paper›PMID 29910195›Full record

ArticleAging2018

A panel of three oxidative stress-related genes predicts overall survival in ovarian cancer patients received platinum-based chemotherapy.

Jin Zhang, Lixiao Yang, Xiaohong Xiang, Zhuoying Li, Kai Qu, Ke Li

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

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  13. Association of variations in theFrontiers in pharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jin Zhang *Department of Clinical Laboratory, Liaocheng People's Hospital, Taishan Medical College, Liaocheng, Shandong Province 252000, China.
Lixiao Yang *Department of Obstetrics and Gynecology, Liaocheng People's Hospital, Taishan Medical College, Liaocheng, Shandong Province 252000, China.
Xiaohong XiangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, China.
Zhuoying LiDepartment of Breast Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, China.
Kai QuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, China.
Ke LiDepartment of Central Laboratory, Liaocheng People's Hospital, Taishan Medical College, Liaocheng, Shandong Province 252000, China.
First Affiliated Hospital of Xi'an Jiaotong University · CNLiaocheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer yields the highest mortality rate of all lethal gynecologic cancers, and the prognosis is unsatisfactory with the major obstacle in resistance to chemotherapy. The generation of reactive oxygen species (ROS) in tumor tissues was associated with chemotherapeutic effectiveness by mediating cellular longevity. In this study, we screened the prognostic values of oxidative stress-related genes in ovarian cancer patients received platinum-based chemotherapy, and conducted a prognostic gene signature composing of three genes,

Indexed as

alpha-GalactosidaseAntineoplastic AgentsBiomarkersFemaleGene Expression RegulationGlutathione TransferaseHumansMiddle AgedOvarian NeoplasmsOxidative StressReproducibility of ResultsSurvival AnalysisThioredoxin Reductase 1alpha-GalactosidaseAntineoplastic AgentsBiomarkersGLA protein, humanGlutathione TransferaseGSTZ1 protein, humanThioredoxin Reductase 1TXNRD1 protein, humanchemotherapyovarian canceroxidative stressplatinumprognosis

Identifiers

PMID29910195
PMCPMC6046245
OpenAlexW2809065472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.