Evidence map›Paper›PMID 29910137›Full record

GuidelineJournal of the American Medical Directors Association2018

The Development of a Decision Tool for the Empiric Treatment of Suspected Urinary Tract Infection in Frail Older Adults: A Delphi Consensus Procedure.

Laura W van Buul, Hilde L Vreeken, Suzanne F Bradley, Christopher J Crnich, Paul J Drinka, Suzanne E Geerlings, Robin L P Jump, Lona Mody, Joseph J Mylotte, Mark Loeb and 8 more

Open access · greenAbstract readPractice Guideline
In one paragraph

Guideline in Journal of the American Medical Directors Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 79 citations in OpenAlex.

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  12. Temporal Trends ofAntibiotics (Basel, Switzerland) · 2025
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  13. Review
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  15. Antibiotics (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Observational
  18. Review
  19. A tale of two bladders: Understanding common bladder issues in primary care.Canadian family physician Medecin de famille canadien · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 14 institutions in 5 countries.

Laura W van BuulDepartment of General Practice and Old Age Medicine, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: L.vanbuul@vumc.nl.
Hilde L VreekenDutch Association of Elderly Care Physicians, Utrecht, The Netherlands.
Suzanne F BradleyInfectious Diseases Section, Veterans Affairs Ann Arbor Healthcare System and the University of Michigan Medical School, Ann Arbor, MI.
Christopher J CrnichUniversity of Wisconsin School of Medicine and Public Health, Madison, WI; Medical Service, William S. Middleton VA Hospital, Madison, WI.
Paul J DrinkaDepartment of Internal Medicine, Geriatrics University of Wisconsin, Madison, WI.
Suzanne E GeerlingsDivision Infectious Diseases, Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Robin L P JumpGeriatric Research, Education and Clinical Center and Specialty Care Center of Innovation at the Louis Stokes Cleveland Department of Veterans Affairs Medical Center (LSCVAMC), Cleveland, OH; Division of Infectious Diseases and HIV Medicine, Department of Medicine and Department of Epidemiology and Biostatistics at Case Western Reserve University School of Medicine, Cleveland, OH.
Lona ModyUniversity of Michigan and Geriatrics Research Education and Clinical Care, VA Ann Arbor Healthcare System, Ann Arbor, MI.
Joseph J MylotteDivision of Infectious Diseases, Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY.
Mark LoebDepartment of Pathology and Molecular Medicine and Institute for Infectious Diseases Research, McMaster University, Hamilton, Canada.
David A NaceDivision of Geriatric Medicine, University of Pittsburgh, Pittsburgh, PA.
Lindsay E NicolleUniversity of Manitoba, Winnipeg, Canada.
Philip D SloaneDepartment of Family Medicine and Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Rhonda L StuartMonash Infectious Diseases, Monash Health, Clayton, Victoria, Australia; Monash University, Victoria, Australia; National Centre for Antimicrobial Stewardship, Victoria, Australia.
Pär-Daniel SundvallNärhälsan, Research and Development Primary Health Care Region Västra Götaland, R&D Center Södra Älvsborg, Sweden; The Sahlgrenska Academy at the University of Gothenburg, Sweden.
Peter UllerydDepartment of Communicable Disease Control, Region Västra Götaland, Sweden.
Ruth B VeenhuizenDepartment of General Practice and Old Age Medicine, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands.
Cees M P M HertoghDepartment of General Practice and Old Age Medicine, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands.
Amsterdam UMC Location VUmc · NLRegion Västra Götaland · SEAcademic Medical Center · NLCase Western Reserve University · USMcMaster University · CAMonash Health · AUUniversity at Buffalo, State University of New York · USUniversity of Manitoba · CAUniversity of Michigan–Ann Arbor · USUniversity of North Carolina at Chapel Hill · USUniversity of Pittsburgh · USUniversity of Wisconsin–Madison · USVA Ann Arbor Healthcare System · USWilliam S. Middleton Memorial Veterans Hospital · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
AHRQ HHS R18 HS023779NIA NIH HHS P30 AG024827
6 · The paper itself

Abstract

objectivesNonspecific signs and symptoms combined with positive urinalysis results frequently trigger antibiotic therapy in frail older adults. However, there is limited evidence about which signs and symptoms indicate urinary tract infection (UTI) in this population. We aimed to find consensus among an international expert panel on which signs and symptoms, commonly attributed to UTI, should and should not lead to antibiotic prescribing in frail older adults, and to integrate these findings into a decision tool for the empiric treatment of suspected UTI in this population.

designA Delphi consensus procedure. SETTING AND

participantsAn international panel of practitioners recognized as experts in the field of UTI in frail older patients. MEASURES: In 4 questionnaire rounds, the panel (1) evaluated the likelihood that individual signs and symptoms are caused by UTI, (2) indicated whether they would prescribe antibiotics empirically for combinations of signs and symptoms, and (3) provided feedback on a draft decision tool.

resultsExperts agreed that the majority of nonspecific signs and symptoms should be evaluated for other causes instead of being attributed to UTI and that urinalysis should not influence treatment decisions unless both nitrite and leukocyte esterase are negative. These and other findings were incorporated into a decision tool for the empiric treatment for suspected UTI in frail older adults with and without an indwelling urinary catheter.

conclusionsA decision tool for suspected UTI in frail older adults was developed based on consensus among an international expert panel. Studies are needed to evaluate whether this decision tool is effective in reaching its aim: the improvement of diagnostic evaluation and treatment for suspected UTI in frail older adults.

Indexed as

Decision Support Systems, ClinicalFrail ElderlyUrinary Tract InfectionsAdultAgedAnti-Bacterial AgentsConsensusDelphi TechniqueFemaleHumansLikelihood FunctionsMaleMiddle AgedSurveys and QuestionnairesAnti-Bacterial Agentsantibiotic prescribingfrail older adultsnonspecific signs and symptomsurinalysisUrinary tract infection

Identifiers

PMID29910137
PMCPMC8048094
OpenAlexW2808526795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.