ReviewJournal of substance abuse treatment2018
Developing an opioid use disorder treatment cascade: A review of quality measures.
Review in Journal of substance abuse treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04804072 (INTEGRA), which is not on this map. Cited by 108 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit to Link Persons Who Inject Drugs to Integrated Care and Prevention for Addiction, HIV, HCV and Primary Care
Who cites it
108 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Factors Associated with Long-Term Retention in Buprenorphine-Based Addiction Treatment Programs: a Systematic Review.Journal of general internal medicine · 2022Pooled it
- Global patterns of opioid use and dependence: harms to populations, interventions, and future action.Lancet (London, England) · 2019Pooled it
- Trial
- Optimizing opioid use disorder treatment with naltrexone or buprenorphine.Drug and alcohol dependence · 2021Trial
- Elevating Patient Voices to Improve Opioid Use Disorder Quality Measurement: A Survey Protocol.Substance use & addiction journal · 2026Article
- Opioid Use Disorder and Evidence-Based Care Among Medicaid-Enrolled Youths.JAMA network open · 2026Article
- The Behavioral Health Treatment Engagement and Retention Learning Collaborative to Improve Receipt and Continuity of Medication Treatment for Opioid Use Disorder.Substance use & addiction journal · 2026Article
- Implementation Outcomes of Low Threshold Care for Persons with Opioid Use Disorders.Journal of general internal medicine · 2026Article
- Cascade of Care for Opioid Use Disorder Among Medicaid Beneficiaries.JAMA network open · 2026Article
- Making Sense of Implementation Science Planning Tools: Addressing Implementation Challenges in Substance Use Disorder and Mental Health Treatment.Global implementation research and applications · 2026Review
- Variation in the quality of opioid use disorder treatment in the Medicaid population in 2019.PloS one · 2026Article
- Article
- The Development of a Patient-Centered Digital Health Care Technology for Young Adults in Opioid Use Disorder Treatment: Qualitative Study.JMIR formative research · 2025Article
- Investigating heterogeneous effects of an expanded methadone access policy with opioid treatment program retention: a Rhode Island population-based retrospective cohort study.American journal of epidemiology · 2025Article
- Racial Inequality in Receipt of Medications for Opioid Use Disorder in Nationwide Outpatient Settings-A Cross-sectional Study.Journal of general internal medicine · 2025Observational
- Tailored Therapies in Addiction Medicine: Redefining Opioid Use Disorder Treatment with Precision Medicine.Journal of personalized medicine · 2025Review
- "It's more than just the act of not using. It's a feeling of finally completing something.": Person-centered definitions of successful treatment outcomes from patients and staff at a methadone treatment program in Baltimore City.Journal of substance use and addiction treatment · 2025Article
- Assessing inequities in buprenorphine treatment across the care cascade.Drug and alcohol dependence · 2025Observational
- Advancing Health Equity Through Substance Use Medical Record Data Sharing: Insights from Healthcare Providers.International journal of environmental research and public health · 2025Article
- Framework for opioid use disorder screening and diagnosis in carceral settings.The International journal on drug policy · 2024Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
backgroundDespite increasing opioid overdose mortality, problems persist in the availability and quality of treatment for opioid use disorder (OUD). Three FDA-approved medications (methadone, buprenorphine, and naltrexone) have high quality evidence supporting their use, but most individuals with OUD do not receive them and many experience relapse following care episodes. Developing and organizing quality measures under a unified framework such as a Cascade of Care could improve system level practice and treatment outcomes. In this context, a review was performed of existing quality measures relevant to the treatment of OUD and the literature assessing the utility of these measures in community practice.
methodsSystematic searches of two national quality measure clearinghouses (National Quality Forum and Agency for Healthcare Research and Quality) were performed for measures that can be applied to the treatment of OUD. Measures were categorized as structural, process, or outcome measures. Second stage searches were then performed within Ovid/Medline focused on published studies investigating the feasibility, reliability, and validity of identified measures, predictors of their satisfaction, and related clinical outcomes.
resultsSeven quality measures were identified that are applicable to the treatment of OUD. All seven were process measures that assess patterns of service delivery. One recently approved measure addresses retention in medication-assisted treatment for patients with OUD. Twenty-nine published studies were identified that evaluate the quality measures, primarily focused on initiation and engagement in care for addiction treatment generally. Most measures and related studies do not specifically incorporate the evidence base for the treatment of OUD or assess patient level outcomes such as overdose.
conclusionDespite considerable progress, gaps exist in quality measures for OUD treatment. Development of a unified quality measurement framework such as an OUD Treatment Cascade will require further elaboration and refinement of existing measures across populations and settings. Such a framework could form the basis for applying strategies at clinical, organizational, and policy levels to expand access to quality care and reduce opioid-related mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.