Trial reportEBioMedicine2018
A Novel Tracheobronchial Stent Loaded with
Trial report in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03944408 (The Efficacy and Safety of a Metal Bare Stent With 125I Seeds for the Treatment of Malignant Central Airway Compared to a Metal Bare Stent), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Efficacy and Safety of a Metal Bare Stent With 125I Seeds for the Treatment of Malignant Central Airway Compared to a Metal Bare Stent: A Multicentric Randomized Controlled Study.
Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- Development of a phased discharge planning for patients undergoing airway stenting: a Delphi study informed by the timing it right framework.Frontiers in medicine · 2026Article
- EBUS-guided Iodine-125 seed implantation in lymph node as a novel therapy for MCAO: A case report.Medicine · 2025Article
- Advances in studies on tracheal stent design addressing the related complications.Materials today. Bio · 2024Review
- Treatment of malignant airway obstruction with Y-shape sigma stent loaded with IBMC pulmonary medicine · 2024Article
- Recent progress in radioactive seed implantation brachytherapy of non-small cell lung cancer: a narrative review.Journal of thoracic disease · 2024Review
- Review of brachytherapy clinical trials: a cross-sectional analysis of ClinicalTrials.gov.Radiation oncology (London, England) · 2024Review
- Analysis of risk factors for pneumothorax after particle implantation in the treatment of advanced lung cancer after surgery and establishment of a nomogram prediction model.Frontiers in medicine · 2024Article
- Treatment of recurrent tracheal adenoid cystic carcinoma with a covered airway stent loaded with Iodine-125 seeds: a 5-year follow-up case report.Frontiers in oncology · 2024Article
- Stent loaded with radioactive Iodine-125 seeds for adenoid cystic carcinoma of central airway: A case report of innovative brachytherapy.Frontiers in oncology · 2023Article
- Transarterial infusion chemotherapy for advanced esophageal cancer with airway stenosis.Frontiers in oncology · 2023Article
- Animal study of a newly designed metal airway brachytherapy stent loaded with radioactiveJournal of cancer research and clinical oncology · 2022Article
- A narrative review of progress in airway stents.Journal of thoracic disease · 2022Review
- Establishing a novel model of malignant airway stenosis in rabbit.Frontiers in oncology · 2022Article
- Radioactive Iodine-125 in Tumor Therapy: Advances and Future Directions.Frontiers in oncology · 2021Review
- Computed tomography-guided implantation ofJournal of contemporary brachytherapy · 2020Article
- The efficacy of the combination of percutaneous transhepatic biliary drainage andJournal of contemporary brachytherapy · 2020Article
- Customizable airway stents-personalized medicine reaches the airways.Journal of thoracic disease · 2019Article
- Radiomics Facilitates Candidate Selection for Irradiation Stents Among Patients With Unresectable Pancreatic Cancer.Frontiers in oncology · 2019Article
- Conventional Versus Therapeutic Stents for Airway Malignancies: Novel Local Therapies Underway.EBioMedicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the safety and efficacy of a novel radioactive bare metal stent (RBMS) compared with a conventional bare metal stent (CBMS) in patients with inoperable malignant airway obstruction.
methodsThis prospective study was approved by the Institutional Ethics Committee, and informed consent was obtained from each participant. Patients with malignant airway obstruction who had dyspnea were randomly assigned to receive RBMS or CBMS placement. The primary endpoint was stenosis grade, while the secondary endpoints were technical success, overall survival, and complications. A p value of <0·05 was considered statistically significant.
resultsBetween September 2013 and July 2015, 66 patients with inoperable malignant airway obstruction received stent placement fluoroscopically (33 in either group). The median follow-up time was 154 days (range, 15-335 days). The baseline stenosis was immediately relieved in both groups after stent placement, and the stenosis grades in the RBMS group were significantly lower than that in the CBMS group since the second month (p < 0·05). The technical success rates of stent placement were 100% in both groups. The median survival in the RBMS group was significantly longer than that in the CBMS group (170 days vs. 123 days, p < 0·05). There was no significant difference in the incidence of complications between the two groups (p < 0·05).
conclusionsThe placement of RBMS in patients with inoperable malignant airway obstruction is feasible and safe, and it significantly reduces restenosis and improves overall survival compared with the placement of CBMS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.