Evidence map›Paper›PMID 29907941›Full record

ArticleObesity surgery2018

The Clinical Outcome of Postoperative Invasive Fungal Infections Complicating Laparoscopic Sleeve Gastrectomy.

Yoav Bichovsky, Leonid Koyfman, Michael Friger, Boris Kirshtein, Abraham Borer, Gilbert Sebbag, Dmitry Frank, Amit Frenkel, Jochanan G Peiser, Moti Klein and 1 more

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yoav BichovskyDepartment of Anesthesiology and Critical Care, General Intensive Care Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Leonid KoyfmanDepartment of Anesthesiology and Critical Care, General Intensive Care Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Michael FrigerHealth Science Faculty, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Boris KirshteinDepartment of General Surgery A, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Abraham BorerDepartment of Infectious Diseases, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Gilbert SebbagDepartment of General Surgery B, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Dmitry FrankDepartment of Anesthesiology and Critical Care, General Intensive Care Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Amit FrenkelDepartment of Anesthesiology and Critical Care, General Intensive Care Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Jochanan G PeiserDepartment of Medical Management, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Moti KleinDepartment of Anesthesiology and Critical Care, General Intensive Care Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Evgeni BrotfainDepartment of Anesthesiology and Critical Care, General Intensive Care Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel. bem1975@gmail.com.ORCID 0000-0002-1353-9852
Ben-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePeritonitis is a major complication of bariatric surgery due to direct damage to the natural barriers to infection. Most such secondary peritoneal infections are caused by Gram-negative microorganisms; however, under certain conditions, Candida species can infect the peritoneal cavity following bariatric surgery. MATERIALS AND

methodsWe retrospectively analyzed the clinical and microbiological data of morbidly obese patients who suffered infectious complications following laparoscopic sleeve gastrectomy (LSG) at the Soroka Medical Center between January 2010 and June 2015.

resultsOut of 800 patients who underwent LSG, 43 (5.3%( developed secondary peritonitis and were admitted to our General Intensive Care Unit during the study period. Intraperitoneal leaks, intraabdominal abscesses and pleural effusions were significantly more common in patients with fungal infection than in those with non-fungal infections (p values 0.027, < 0.001, and < 0.014, respectively). Leaks situated at the suture line of gastro-esophageal area occurred much more frequently in the fungal infection group than in the non-fungal infection group (94.7 vs 41.7%, p < 0.001). Microbiological analysis of the abdominal and pleural fluids of patients with invasive fungal infectious complications showed the presence of commensal polymicrobial bacterial infections-mainly Streptoccocus constellatus and coagulase negative Staphylococcus spp. Leakage at the suture line of gastro-esophageal area (upper suture part) and administration of parenteral nutrition were found to be independent predictors for invasive fungal infections after LSG.

conclusionOur study demonstrates that invasive fungal infection is a significant postoperative infectious complication of bariatric LSG surgery in morbidly obese patients.

Indexed as

AdultFemaleGastrectomyHumansInvasive Fungal InfectionsLaparoscopyMaleMiddle AgedMorbidityObesity, MorbidPeritonitisPostoperative ComplicationsPostoperative PeriodPrognosisRetrospective StudiesTreatment OutcomeCritical careInvasive fungal infectionObesitySleeve gastrectomy

Identifiers

PMID29907941
OpenAlexW2808515805

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.