ArticleMucosal immunology2018
BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability.
Abstract read
In one paragraph
Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
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The trial behind it
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- State-of-the-Art Review on Probiotics, Synbiotics, and Microbial Metabolites: Molecular Mechanisms Shaping Host Immunity, Metabolic Health, and Chronic Disease Prevention.Molecular nutrition & food research · 2026Review
- Article
- A Review of the Influence of Prebiotics, Probiotics, Synbiotics, and Postbiotics on the Human Gut Microbiome and Intestinal Integrity.Journal of clinical medicine · 2025Review
- LncRNACentral-European journal of immunology · 2024Article
- HOXD10 regulates intestinal permeability and inhibits inflammation of dextran sulfate sodium-induced ulcerative colitis through the inactivation of the Rho/ROCK/MMPs axis.Open medicine (Warsaw, Poland) · 2024Article
- Dysregulated expression of IGSF11-AS1 and BVES-AS in azoospermia and its correlation with serum hormone levels.Biomarkers in medicine · 2024Article
- Modulation of POPDC1 Expression by Phenothiazine and Trifluoperazine Suppress Colon Cancer Growth and Migration.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice.American journal of physiology. Gastrointestinal and liver physiology · 2021Article
- The Transition from Gastric Intestinal Metaplasia to Gastric Cancer InvolvesInternational journal of molecular sciences · 2021Article
- Microbiome Crosstalk in Immunotherapy and Antiangiogenesis Therapy.Frontiers in immunology · 2021Review
- Ten years of research on the role of BVES/ POPDC1 in human disease: a review.OncoTargets and therapy · 2019Review
- A Novel Postbiotic FromFrontiers in microbiology · 2019Article
- Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk.Frontiers in physiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 4 institutions in 2 countries.
Yash A ChoksiDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Vishruth K ReddyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kshipra SinghDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Caitlyn W BarrettDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Sarah P ShortDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Bobak ParangDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Cody E KeatingDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua J ThompsonDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Thomas G VerriereDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Rachel E BrownDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
M Blanca PiazueloDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
David M BaderDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
M Kay WashingtonDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Mukul K MittalDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Thomas BrandDevelopmental Dynamics, Heart Science Centre, Imperial College London, London, UK.
Alain P GobertDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Lori A CoburnDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Keith T WilsonDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Christopher S WilliamsDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. christopher.s.williams@vanderbilt.edu.
Vanderbilt University · USVanderbilt University Medical Center · USImperial College London · GBVA Tennessee Valley Healthcare System · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8MVanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7MThe Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4MUnderstanding and Controlling p120 Dysfunction in CRCP50CA095103 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COFFEY, ROBERT J. · 2002 to 2017
$33.6MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MVanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3MTRANSGENIC MOUSE/ ES CELL SHARES RESOURCESP60DK020593 · NIDDK · VANDERBILT UNIVERSITY · PI MCGUINNESS, OWEN P · 1986 to 2011
$28.1MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3MVanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STEPHEN W. FESIK · 2019 to 2026
$19.6MShop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 1989 to 2026
$19.6MVanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9MTRAINING IN GASTROENTEROLOGYT32DK007673 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 1992 to 2026
$8.4MBLRD VA I01 BX001426BLRD VA I01 BX001453BLRD VA IK2 BX002126British Heart Foundation PG/14/83/31128Medical Research Council MR/J010383/1NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243NCCIH NIH HHS R01 AT004821NCI NIH HHS F31 CA167920NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA095103NCI NIH HHS P50 CA236733NEI NIH HHS P30 EY008126NIDDK NIH HHS F30 DK096718NIDDK NIH HHS F30 DK103498NIDDK NIH HHS F32 DK108492NIDDK NIH HHS K08 DK080221NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK099204NIDDK NIH HHS T32 DK007673NIDDK NIH HHS U24 DK059637NIDDK NIH HHS U2C DK059637NIGMS NIH HHS T32 GM007347NIH HHS S10 OD021630
Abstract
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. There have been no in vivo studies investigating the role of BVES in colitis. We hypothesized that BVES is critical for maintaining colonic epithelial integrity. At baseline, Bves
Indexed as
AdultAnimalsCaco-2 CellsCell Adhesion MoleculesCell LineCell Line, TumorCitrobacter rodentiumCoculture TechniquesColitis, UlcerativeColonDextran SulfateEpithelial CellsEscherichia coliFemaleHEK293 CellsHumansCell Adhesion MoleculesDextran SulfateMembrane ProteinsMuscle ProteinsPOPDC1 protein, humanRNA, Messenger
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.